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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COX4I1
All Species:
7.88
Human Site:
S158
Identified Species:
15.76
UniProt:
P13073
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13073
NP_001852.1
169
19577
S158
N
P
I
Q
G
L
A
S
K
W
D
Y
E
K
N
Chimpanzee
Pan troglodytes
O46577
144
16844
K134
P
I
Q
G
L
A
S
K
W
D
Y
E
K
N
E
Rhesus Macaque
Macaca mulatta
XP_001113518
169
19775
S158
N
P
I
Q
G
L
A
S
K
W
D
Y
E
K
N
Dog
Lupus familis
XP_536759
169
19557
A158
S
P
I
Q
G
F
S
A
K
W
D
Y
D
K
N
Cat
Felis silvestris
Mouse
Mus musculus
P19783
169
19512
A158
N
P
I
Q
G
F
S
A
K
W
D
Y
D
K
N
Rat
Rattus norvegicus
P10888
169
19496
A158
N
P
I
Q
G
F
S
A
K
W
D
Y
N
K
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507221
169
19525
A158
N
P
I
E
G
F
S
A
K
W
D
Y
E
K
N
Chicken
Gallus gallus
NP_001025748
171
19613
A160
N
P
V
E
G
I
S
A
Q
W
D
Y
E
K
N
Frog
Xenopus laevis
NP_001087184
169
19411
A158
N
P
V
Q
G
F
S
A
Q
W
D
Y
E
K
N
Zebra Danio
Brachydanio rerio
NP_999866
169
19367
A158
N
P
V
Q
G
F
A
A
K
W
D
Y
E
N
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610013
182
20501
S171
N
P
V
T
G
L
T
S
K
W
D
Y
E
N
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796538
162
18668
Q152
P
V
T
G
I
A
S
Q
W
D
Y
E
K
N
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.2
94
82.8
N.A.
78.1
79.8
N.A.
73.9
69
65
63.3
N.A.
34
N.A.
N.A.
37.2
Protein Similarity:
100
85.2
97
95.8
N.A.
89.9
92.3
N.A.
89.9
88.8
84.6
79.2
N.A.
50.5
N.A.
N.A.
56.8
P-Site Identity:
100
0
100
66.6
N.A.
73.3
73.3
N.A.
73.3
60
66.6
73.3
N.A.
66.6
N.A.
N.A.
0
P-Site Similarity:
100
13.3
100
93.3
N.A.
93.3
86.6
N.A.
93.3
100
93.3
86.6
N.A.
73.3
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
17
25
59
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
17
84
0
17
0
0
% D
% Glu:
0
0
0
17
0
0
0
0
0
0
0
17
59
0
17
% E
% Phe:
0
0
0
0
0
50
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
17
84
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
50
0
9
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
9
67
0
0
0
17
67
9
% K
% Leu:
0
0
0
0
9
25
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
75
0
0
0
0
0
0
0
0
0
0
0
9
34
75
% N
% Pro:
17
84
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
9
59
0
0
0
9
17
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
0
0
0
0
0
67
25
0
0
0
0
0
0
0
% S
% Thr:
0
0
9
9
0
0
9
0
0
0
0
0
0
0
0
% T
% Val:
0
9
34
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
17
84
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
17
84
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _