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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: COX4I1 All Species: 20.91
Human Site: S30 Identified Species: 41.82
UniProt: P13073 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P13073 NP_001852.1 169 19577 S30 A H E S V V K S E D F S L P A
Chimpanzee Pan troglodytes O46577 144 16844 L10 V K S E D F S L P A Y M D R R
Rhesus Macaque Macaca mulatta XP_001113518 169 19775 S30 A H E S V V K S E D F S L P A
Dog Lupus familis XP_536759 169 19557 S30 A H G S V V K S E D F A L P S
Cat Felis silvestris
Mouse Mus musculus P19783 169 19512 S30 A H G S V V K S E D Y A F P T
Rat Rattus norvegicus P10888 169 19496 S30 A H G S V V K S E D Y A L P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507221 169 19525 T30 G H A G V V K T E E Y S L P S
Chicken Gallus gallus NP_001025748 171 19613 V30 A H G H A G V V K A D D F S H
Frog Xenopus laevis NP_001087184 169 19411 P30 G H A G V V K P E T Y S L P I
Zebra Danio Brachydanio rerio NP_999866 169 19367 V30 G A H G V A K V E D Y S L P A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610013 182 20501 Y44 G K R E I V G Y G W N G T A C
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796538 162 18668 L28 K R N F H D K L Y A D R L D Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.2 94 82.8 N.A. 78.1 79.8 N.A. 73.9 69 65 63.3 N.A. 34 N.A. N.A. 37.2
Protein Similarity: 100 85.2 97 95.8 N.A. 89.9 92.3 N.A. 89.9 88.8 84.6 79.2 N.A. 50.5 N.A. N.A. 56.8
P-Site Identity: 100 0 100 80 N.A. 66.6 73.3 N.A. 53.3 13.3 53.3 53.3 N.A. 6.6 N.A. N.A. 13.3
P-Site Similarity: 100 6.6 100 93.3 N.A. 80 93.3 N.A. 80 20 60 60 N.A. 13.3 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 50 9 17 0 9 9 0 0 0 25 0 25 0 9 25 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % C
% Asp: 0 0 0 0 9 9 0 0 0 50 17 9 9 9 0 % D
% Glu: 0 0 17 17 0 0 0 0 67 9 0 0 0 0 0 % E
% Phe: 0 0 0 9 0 9 0 0 0 0 25 0 17 0 0 % F
% Gly: 34 0 34 25 0 9 9 0 9 0 0 9 0 0 0 % G
% His: 0 67 9 9 9 0 0 0 0 0 0 0 0 0 9 % H
% Ile: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 9 % I
% Lys: 9 17 0 0 0 0 75 0 9 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 17 0 0 0 0 67 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % M
% Asn: 0 0 9 0 0 0 0 0 0 0 9 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 9 9 0 0 0 0 67 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 9 9 0 0 0 0 0 0 0 0 9 0 9 9 % R
% Ser: 0 0 9 42 0 0 9 42 0 0 0 42 0 9 25 % S
% Thr: 0 0 0 0 0 0 0 9 0 9 0 0 9 0 9 % T
% Val: 9 0 0 0 67 67 9 17 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 9 9 0 50 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _