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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COX4I1
All Species:
34.55
Human Site:
S74
Identified Species:
69.09
UniProt:
P13073
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13073
NP_001852.1
169
19577
S74
K
A
S
W
S
S
L
S
M
D
E
K
V
E
L
Chimpanzee
Pan troglodytes
O46577
144
16844
D51
S
W
S
S
L
S
M
D
E
K
V
E
L
Y
R
Rhesus Macaque
Macaca mulatta
XP_001113518
169
19775
S74
K
A
S
W
S
S
L
S
M
D
E
K
V
E
L
Dog
Lupus familis
XP_536759
169
19557
S74
K
A
S
W
S
S
L
S
I
D
E
K
V
E
L
Cat
Felis silvestris
Mouse
Mus musculus
P19783
169
19512
S74
K
A
D
W
S
S
L
S
R
D
E
K
V
Q
L
Rat
Rattus norvegicus
P10888
169
19496
S74
K
A
D
W
S
S
L
S
R
D
E
K
V
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507221
169
19525
S74
K
A
A
W
S
S
L
S
N
D
E
K
L
G
L
Chicken
Gallus gallus
NP_001025748
171
19613
S76
K
A
S
W
T
A
L
S
V
D
E
K
V
E
L
Frog
Xenopus laevis
NP_001087184
169
19411
S74
K
G
A
W
A
S
L
S
S
K
E
K
L
D
L
Zebra Danio
Brachydanio rerio
NP_999866
169
19367
S74
K
G
S
W
A
A
L
S
K
E
E
K
I
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610013
182
20501
S87
Q
G
D
W
K
K
L
S
T
Q
E
I
K
A
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796538
162
18668
A69
D
W
K
A
L
T
Q
A
D
K
K
E
L
Y
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.2
94
82.8
N.A.
78.1
79.8
N.A.
73.9
69
65
63.3
N.A.
34
N.A.
N.A.
37.2
Protein Similarity:
100
85.2
97
95.8
N.A.
89.9
92.3
N.A.
89.9
88.8
84.6
79.2
N.A.
50.5
N.A.
N.A.
56.8
P-Site Identity:
100
13.3
100
93.3
N.A.
80
80
N.A.
73.3
80
53.3
53.3
N.A.
33.3
N.A.
N.A.
0
P-Site Similarity:
100
33.3
100
100
N.A.
86.6
86.6
N.A.
86.6
100
80
80
N.A.
40
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
59
17
9
17
17
0
9
0
0
0
0
0
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
25
0
0
0
0
9
9
59
0
0
0
9
0
% D
% Glu:
0
0
0
0
0
0
0
0
9
9
84
17
0
34
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
25
0
0
0
0
0
0
0
0
0
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
9
0
0
9
9
0
0
% I
% Lys:
75
0
9
0
9
9
0
0
9
25
9
75
9
0
0
% K
% Leu:
0
0
0
0
17
0
84
0
0
0
0
0
34
0
84
% L
% Met:
0
0
0
0
0
0
9
0
17
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
9
0
0
0
0
0
9
0
0
9
0
0
0
17
0
% Q
% Arg:
0
0
0
0
0
0
0
0
17
0
0
0
0
0
17
% R
% Ser:
9
0
50
9
50
67
0
84
9
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
9
9
0
0
9
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
9
0
9
0
50
0
0
% V
% Trp:
0
17
0
84
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
17
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _