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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IFI30 All Species: 5.45
Human Site: S250 Identified Species: 10.91
UniProt: P13284 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P13284 NP_006323 261 29149 S250 K K P D V C P S S T S S L R S
Chimpanzee Pan troglodytes XP_001162304 289 32206 P278 K K P D V C P P S T S S L R S
Rhesus Macaque Macaca mulatta XP_001114116 250 27904 P239 E K P D I C P P S T H S L R G
Dog Lupus familis XP_533874 223 25111 T213 K P D A C Q L T A T S Q R K V
Cat Felis silvestris
Mouse Mus musculus NP_075552 248 27766 S236 T E K P D I C S S I A D S P R
Rat Rattus norvegicus NP_001025197 248 27626 S236 T E K P D I C S S M A D A P R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511104 261 29112 P243 K L Y K G Q K P S A C L S N S
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001006057 255 28308 P238 S L Y K G Q K P A A C T L G L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O17861 277 30825 E261 D K A I P Y C E A A L K L K Y
Sea Urchin Strong. purpuratus XP_001203858 210 23096 T200 G V K P A G C T Q E G R M R S
Poplar Tree Populus trichocarpa XP_002318774 269 30165 C229 G K S L P K T C S S H P N T S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_567395 232 26283 F222 Y E R K V S K F Q V S Y V D E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.9 87.7 60.9 N.A. 59.7 61.2 N.A. 46.7 N.A. N.A. 37.1 N.A. N.A. N.A. 28.1 35.2
Protein Similarity: 100 89.9 91.9 72.8 N.A. 72 71.6 N.A. 63.2 N.A. N.A. 55.5 N.A. N.A. N.A. 46.5 47.1
P-Site Identity: 100 93.3 66.6 20 N.A. 13.3 13.3 N.A. 20 N.A. N.A. 6.6 N.A. N.A. N.A. 13.3 13.3
P-Site Similarity: 100 93.3 80 40 N.A. 26.6 26.6 N.A. 20 N.A. N.A. 20 N.A. N.A. N.A. 26.6 26.6
Percent
Protein Identity: 33.4 N.A. N.A. 33.7 N.A. N.A.
Protein Similarity: 52.4 N.A. N.A. 51.3 N.A. N.A.
P-Site Identity: 20 N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: 26.6 N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 9 9 0 0 0 25 25 17 0 9 0 0 % A
% Cys: 0 0 0 0 9 25 34 9 0 0 17 0 0 0 0 % C
% Asp: 9 0 9 25 17 0 0 0 0 0 0 17 0 9 0 % D
% Glu: 9 25 0 0 0 0 0 9 0 9 0 0 0 0 9 % E
% Phe: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % F
% Gly: 17 0 0 0 17 9 0 0 0 0 9 0 0 9 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 17 0 0 0 0 % H
% Ile: 0 0 0 9 9 17 0 0 0 9 0 0 0 0 0 % I
% Lys: 34 42 25 25 0 9 25 0 0 0 0 9 0 17 0 % K
% Leu: 0 17 0 9 0 0 9 0 0 0 9 9 42 0 9 % L
% Met: 0 0 0 0 0 0 0 0 0 9 0 0 9 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 9 9 0 % N
% Pro: 0 9 25 25 17 0 25 34 0 0 0 9 0 17 0 % P
% Gln: 0 0 0 0 0 25 0 0 17 0 0 9 0 0 0 % Q
% Arg: 0 0 9 0 0 0 0 0 0 0 0 9 9 34 17 % R
% Ser: 9 0 9 0 0 9 0 25 59 9 34 25 17 0 42 % S
% Thr: 17 0 0 0 0 0 9 17 0 34 0 9 0 9 0 % T
% Val: 0 9 0 0 25 0 0 0 0 9 0 0 9 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 17 0 0 9 0 0 0 0 0 9 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _