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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYF5 All Species: 25.76
Human Site: S176 Identified Species: 43.59
UniProt: P13349 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P13349 NP_005584.2 255 28296 S176 E C N S P V W S R K S S T F D
Chimpanzee Pan troglodytes XP_508311 320 34428 P202 G D S D A S S P R S N C S D G
Rhesus Macaque Macaca mulatta XP_001087187 255 28320 S176 E C N S P V W S R K R S T F D
Dog Lupus familis XP_852162 255 27763 S176 E C N S P V W S R K S S S F D
Cat Felis silvestris
Mouse Mus musculus P24699 255 28211 S176 E C N S P V W S R K N S S F D
Rat Rattus norvegicus Q02346 318 34341 R202 D S D A S S P R S N C S D G M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505422 256 28746 S176 E C N S P V W S R R N S S F D
Chicken Gallus gallus Q08856 258 28438 P178 D S R S P V W P A R G S S F E
Frog Xenopus laevis P24700 255 28624 S176 D C S S P Q W S G R N S S F D
Zebra Danio Brachydanio rerio Q90477 275 30918 T177 M M D F M G P T C Q T R R R N
Tiger Blowfish Takifugu rubipres Q6Q2A8 307 33612 Q205 D F N G P T C Q S N R R G S Y
Fruit Fly Dros. melanogaster P22816 332 36166 L254 G A Y L E D K L S F Y N K H M
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P22980 324 36431 H245 H D Y V T S S H F A S S S Y N
Sea Urchin Strong. purpuratus XP_781762 250 27193 S169 N G D S E M D S A E T S S N T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 46.8 98.8 87.8 N.A. 89.4 46.8 N.A. 84.7 70.9 69.4 51.6 40.7 33.7 N.A. 23.7 45.1
Protein Similarity: 100 58.7 98.8 92.1 N.A. 94.1 58.8 N.A. 92.5 82.1 84.3 63.6 54.7 46.9 N.A. 41.9 58.8
P-Site Identity: 100 6.6 93.3 93.3 N.A. 86.6 6.6 N.A. 80 40 53.3 0 13.3 0 N.A. 13.3 20
P-Site Similarity: 100 26.6 93.3 100 N.A. 100 26.6 N.A. 100 66.6 86.6 33.3 20 6.6 N.A. 33.3 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 8 8 0 0 0 15 8 0 0 0 0 0 % A
% Cys: 0 43 0 0 0 0 8 0 8 0 8 8 0 0 0 % C
% Asp: 29 15 22 8 0 8 8 0 0 0 0 0 8 8 43 % D
% Glu: 36 0 0 0 15 0 0 0 0 8 0 0 0 0 8 % E
% Phe: 0 8 0 8 0 0 0 0 8 8 0 0 0 50 0 % F
% Gly: 15 8 0 8 0 8 0 0 8 0 8 0 8 8 8 % G
% His: 8 0 0 0 0 0 0 8 0 0 0 0 0 8 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 8 0 0 29 0 0 8 0 0 % K
% Leu: 0 0 0 8 0 0 0 8 0 0 0 0 0 0 0 % L
% Met: 8 8 0 0 8 8 0 0 0 0 0 0 0 0 15 % M
% Asn: 8 0 43 0 0 0 0 0 0 15 29 8 0 8 15 % N
% Pro: 0 0 0 0 58 0 15 15 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 8 0 8 0 8 0 0 0 0 0 % Q
% Arg: 0 0 8 0 0 0 0 8 43 22 15 15 8 8 0 % R
% Ser: 0 15 15 58 8 22 15 50 22 8 22 72 58 8 0 % S
% Thr: 0 0 0 0 8 8 0 8 0 0 15 0 15 0 8 % T
% Val: 0 0 0 8 0 43 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 50 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 15 0 0 0 0 0 0 0 8 0 0 8 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _