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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYF5 All Species: 19.39
Human Site: S216 Identified Species: 32.82
UniProt: P13349 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P13349 NP_005584.2 255 28296 S216 N I V D R I T S S E Q P G L P
Chimpanzee Pan troglodytes XP_508311 320 34428 K242 P S E P R P G K S A A V S S L
Rhesus Macaque Macaca mulatta XP_001087187 255 28320 S216 N I V D R I T S S E Q P G L P
Dog Lupus familis XP_852162 255 27763 N216 S I V D R I T N S E Q P G L P
Cat Felis silvestris
Mouse Mus musculus P24699 255 28211 S216 S I V D R I T S T E P S E L A
Rat Rattus norvegicus Q02346 318 34341 S242 S E P R P G K S A A V S S L D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505422 256 28746 S216 S S I V D R I S S C D Q P G L
Chicken Gallus gallus Q08856 258 28438 S218 S S I V D R L S P A E E P G L
Frog Xenopus laevis P24700 255 28624 S216 S I V D R I S S P Q Q C S L P
Zebra Danio Brachydanio rerio Q90477 275 30918 V217 L D C L S S I V E R I S T E T
Tiger Blowfish Takifugu rubipres Q6Q2A8 307 33612 F245 V N N C S A W F C F A G S L K
Fruit Fly Dros. melanogaster P22816 332 36166 T294 Q S I N K S T T S P I Q N K A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P22980 324 36431 S285 V D L R R R N S L D R L S R I
Sea Urchin Strong. purpuratus XP_781762 250 27193 Y209 D V S S P Y G Y N G C G N A S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 46.8 98.8 87.8 N.A. 89.4 46.8 N.A. 84.7 70.9 69.4 51.6 40.7 33.7 N.A. 23.7 45.1
Protein Similarity: 100 58.7 98.8 92.1 N.A. 94.1 58.8 N.A. 92.5 82.1 84.3 63.6 54.7 46.9 N.A. 41.9 58.8
P-Site Identity: 100 13.3 100 86.6 N.A. 60 13.3 N.A. 13.3 6.6 60 0 6.6 13.3 N.A. 13.3 0
P-Site Similarity: 100 13.3 100 100 N.A. 73.3 26.6 N.A. 26.6 26.6 80 0 6.6 40 N.A. 33.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 8 0 0 8 22 15 0 0 8 15 % A
% Cys: 0 0 8 8 0 0 0 0 8 8 8 8 0 0 0 % C
% Asp: 8 15 0 36 15 0 0 0 0 8 8 0 0 0 8 % D
% Glu: 0 8 8 0 0 0 0 0 8 29 8 8 8 8 0 % E
% Phe: 0 0 0 0 0 0 0 8 0 8 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 8 15 0 0 8 0 15 22 15 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 36 22 0 0 36 15 0 0 0 15 0 0 0 8 % I
% Lys: 0 0 0 0 8 0 8 8 0 0 0 0 0 8 8 % K
% Leu: 8 0 8 8 0 0 8 0 8 0 0 8 0 50 22 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 15 8 8 8 0 0 8 8 8 0 0 0 15 0 0 % N
% Pro: 8 0 8 8 15 8 0 0 15 8 8 22 15 0 29 % P
% Gln: 8 0 0 0 0 0 0 0 0 8 29 15 0 0 0 % Q
% Arg: 0 0 0 15 50 22 0 0 0 8 8 0 0 8 0 % R
% Ser: 43 29 8 8 15 15 8 58 43 0 0 22 36 8 8 % S
% Thr: 0 0 0 0 0 0 36 8 8 0 0 0 8 0 8 % T
% Val: 15 8 36 15 0 0 0 8 0 0 8 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 8 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _