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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYF5 All Species: 16.06
Human Site: S246 Identified Species: 27.18
UniProt: P13349 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P13349 NP_005584.2 255 28296 S246 Q P A T P G A S S S R L I Y H
Chimpanzee Pan troglodytes XP_508311 320 34428 A272 A A P A L L L A D V P S E S P
Rhesus Macaque Macaca mulatta XP_001087187 255 28320 S246 Q P A T P G A S S S R L I Y H
Dog Lupus familis XP_852162 255 27763 S246 Q P A T P G A S G S R L I Y H
Cat Felis silvestris
Mouse Mus musculus P24699 255 28211 S246 Q P A T P G P S S S R L I Y H
Rat Rattus norvegicus Q02346 318 34341 D272 A P S L L L P D A P P E S P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505422 256 28746 A246 S Q P G T P G A P N S R L I Y
Chicken Gallus gallus Q08856 258 28438 S248 S G P G T P G S P P P R R T Y
Frog Xenopus laevis P24700 255 28624 H246 L P R S P D A H D C R P I Y H
Zebra Danio Brachydanio rerio Q90477 275 30918 S247 P C S P H E G S V L S D T G T
Tiger Blowfish Takifugu rubipres Q6Q2A8 307 33612 S275 R I S T A T S S G P P P V D G
Fruit Fly Dros. melanogaster P22816 332 36166 V324 T A P T S L H V N F K R K C S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P22980 324 36431 I315 L Q P A N D V I D G E K K L E
Sea Urchin Strong. purpuratus XP_781762 250 27193 P239 K G K A I T S P K K A T S D G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 46.8 98.8 87.8 N.A. 89.4 46.8 N.A. 84.7 70.9 69.4 51.6 40.7 33.7 N.A. 23.7 45.1
Protein Similarity: 100 58.7 98.8 92.1 N.A. 94.1 58.8 N.A. 92.5 82.1 84.3 63.6 54.7 46.9 N.A. 41.9 58.8
P-Site Identity: 100 0 100 93.3 N.A. 93.3 6.6 N.A. 0 6.6 46.6 6.6 13.3 6.6 N.A. 0 0
P-Site Similarity: 100 6.6 100 93.3 N.A. 93.3 20 N.A. 26.6 13.3 53.3 13.3 40 20 N.A. 0 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 15 29 22 8 0 29 15 8 0 8 0 0 0 0 % A
% Cys: 0 8 0 0 0 0 0 0 0 8 0 0 0 8 0 % C
% Asp: 0 0 0 0 0 15 0 8 22 0 0 8 0 15 0 % D
% Glu: 0 0 0 0 0 8 0 0 0 0 8 8 8 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % F
% Gly: 0 15 0 15 0 29 22 0 15 8 0 0 0 8 15 % G
% His: 0 0 0 0 8 0 8 8 0 0 0 0 0 0 36 % H
% Ile: 0 8 0 0 8 0 0 8 0 0 0 0 36 8 0 % I
% Lys: 8 0 8 0 0 0 0 0 8 8 8 8 15 0 0 % K
% Leu: 15 0 0 8 15 22 8 0 0 8 0 29 8 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 0 0 0 8 8 0 0 0 0 0 % N
% Pro: 8 43 36 8 36 15 15 8 15 22 29 15 0 8 15 % P
% Gln: 29 15 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 8 0 8 0 0 0 0 0 0 0 36 22 8 0 0 % R
% Ser: 15 0 22 8 8 0 15 50 22 29 15 8 15 8 8 % S
% Thr: 8 0 0 43 15 15 0 0 0 0 0 8 8 8 8 % T
% Val: 0 0 0 0 0 0 8 8 8 8 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 36 15 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _