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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYF5
All Species:
24.24
Human Site:
Y186
Identified Species:
41.03
UniProt:
P13349
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13349
NP_005584.2
255
28296
Y186
S
S
T
F
D
S
I
Y
C
P
D
V
S
N
V
Chimpanzee
Pan troglodytes
XP_508311
320
34428
D212
N
C
S
D
G
M
M
D
Y
S
G
P
P
S
G
Rhesus Macaque
Macaca mulatta
XP_001087187
255
28320
Y186
R
S
T
F
D
S
I
Y
C
S
D
V
S
N
V
Dog
Lupus familis
XP_852162
255
27763
Y186
S
S
S
F
D
S
I
Y
C
P
D
G
P
N
V
Cat
Felis silvestris
Mouse
Mus musculus
P24699
255
28211
Y186
N
S
S
F
D
S
I
Y
C
P
D
V
S
N
A
Rat
Rattus norvegicus
Q02346
318
34341
Y212
C
S
D
G
M
M
D
Y
S
G
P
P
S
G
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505422
256
28746
Y186
N
S
S
F
D
S
S
Y
C
P
E
I
P
N
V
Chicken
Gallus gallus
Q08856
258
28438
Y188
G
S
S
F
E
A
G
Y
C
R
E
M
P
H
G
Frog
Xenopus laevis
P24700
255
28624
Y186
N
S
S
F
D
N
V
Y
C
S
D
L
Q
T
S
Zebra Danio
Brachydanio rerio
Q90477
275
30918
D187
T
R
R
R
N
S
Y
D
S
S
Y
F
N
D
T
Tiger Blowfish
Takifugu rubipres
Q6Q2A8
307
33612
S215
R
R
G
S
Y
Y
S
S
Y
F
S
Q
T
P
K
Fruit Fly
Dros. melanogaster
P22816
332
36166
Y264
Y
N
K
H
M
E
K
Y
G
Q
F
T
D
F
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P22980
324
36431
N255
S
S
S
Y
N
P
E
N
M
F
D
D
D
D
L
Sea Urchin
Strong. purpuratus
XP_781762
250
27193
A179
T
S
S
N
T
S
D
A
M
T
D
G
S
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.8
98.8
87.8
N.A.
89.4
46.8
N.A.
84.7
70.9
69.4
51.6
40.7
33.7
N.A.
23.7
45.1
Protein Similarity:
100
58.7
98.8
92.1
N.A.
94.1
58.8
N.A.
92.5
82.1
84.3
63.6
54.7
46.9
N.A.
41.9
58.8
P-Site Identity:
100
0
86.6
80
N.A.
80
20
N.A.
60
26.6
40
6.6
0
6.6
N.A.
20
26.6
P-Site Similarity:
100
26.6
86.6
86.6
N.A.
93.3
20
N.A.
86.6
66.6
73.3
33.3
6.6
13.3
N.A.
53.3
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
8
% A
% Cys:
8
8
0
0
0
0
0
0
50
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
43
0
15
15
0
0
50
8
15
15
8
% D
% Glu:
0
0
0
0
8
8
8
0
0
0
15
0
0
0
0
% E
% Phe:
0
0
0
50
0
0
0
0
0
15
8
8
0
8
0
% F
% Gly:
8
0
8
8
8
0
8
0
8
8
8
15
0
8
15
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
0
0
29
0
0
0
0
8
0
0
0
% I
% Lys:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
8
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% L
% Met:
0
0
0
0
15
15
8
0
15
0
0
8
0
0
0
% M
% Asn:
29
8
0
8
15
8
0
8
0
0
0
0
8
36
0
% N
% Pro:
0
0
0
0
0
8
0
0
0
29
8
15
29
8
15
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
8
8
0
0
% Q
% Arg:
15
15
8
8
0
0
0
0
0
8
0
0
0
0
0
% R
% Ser:
22
72
58
8
0
50
15
8
15
29
8
0
36
15
8
% S
% Thr:
15
0
15
0
8
0
0
0
0
8
0
8
8
8
8
% T
% Val:
0
0
0
0
0
0
8
0
0
0
0
22
0
0
29
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
8
8
8
8
65
15
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _