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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LAMP2
All Species:
17.27
Human Site:
Y74
Identified Species:
38
UniProt:
P13473
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13473
NP_002285.1
410
44961
Y74
S
D
H
G
T
V
T
Y
N
G
S
I
C
G
D
Chimpanzee
Pan troglodytes
XP_001144542
375
40516
N61
R
G
H
T
L
T
L
N
F
T
R
N
A
T
R
Rhesus Macaque
Macaca mulatta
XP_001084005
480
52932
Y144
S
D
R
G
T
V
T
Y
N
G
S
I
C
G
D
Dog
Lupus familis
XP_864590
411
45117
Y74
S
D
F
S
T
A
T
Y
N
G
S
V
C
G
N
Cat
Felis silvestris
Mouse
Mus musculus
P17047
415
45629
H70
A
V
P
D
K
A
T
H
D
G
S
S
C
G
D
Rat
Rattus norvegicus
P17046
411
45145
Y70
T
V
P
D
K
V
T
Y
N
G
S
S
C
G
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510101
454
50017
Y115
T
V
P
E
N
V
T
Y
D
G
S
S
C
G
D
Chicken
Gallus gallus
Q90617
425
46697
H73
D
L
T
S
T
V
T
H
N
G
S
I
C
G
S
Frog
Xenopus laevis
NP_001087881
415
44810
T74
P
V
P
S
D
V
T
T
N
G
S
S
C
G
S
Zebra Danio
Brachydanio rerio
NP_955996
411
43489
S70
A
S
V
S
E
R
S
S
C
G
S
A
A
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789418
489
51961
Q128
T
I
P
F
M
L
P
Q
G
A
M
V
D
T
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
34.1
79.5
84.1
N.A.
65.3
66.9
N.A.
57
45.8
43.3
35.7
N.A.
N.A.
N.A.
N.A.
25.3
Protein Similarity:
100
54.1
82
89.7
N.A.
77.3
78.5
N.A.
70.9
63.5
60.7
56.4
N.A.
N.A.
N.A.
N.A.
41.7
P-Site Identity:
100
6.6
93.3
66.6
N.A.
40
60
N.A.
53.3
60
46.6
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
6.6
93.3
80
N.A.
60
66.6
N.A.
66.6
66.6
46.6
26.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
0
0
0
19
0
0
0
10
0
10
19
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
73
0
0
% C
% Asp:
10
28
0
19
10
0
0
0
19
0
0
0
10
0
46
% D
% Glu:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
10
10
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
10
0
19
0
0
0
0
10
82
0
0
0
73
0
% G
% His:
0
0
19
0
0
0
0
19
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
0
0
0
28
0
0
0
% I
% Lys:
0
0
0
0
19
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
0
0
10
10
10
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
10
% M
% Asn:
0
0
0
0
10
0
0
10
55
0
0
10
0
0
10
% N
% Pro:
10
0
46
0
0
0
10
0
0
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
10
0
10
0
0
10
0
0
0
0
10
0
0
0
10
% R
% Ser:
28
10
0
37
0
0
10
10
0
0
82
37
0
0
19
% S
% Thr:
28
0
10
10
37
10
73
10
0
10
0
0
0
19
0
% T
% Val:
0
37
10
0
0
55
0
0
0
0
0
19
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
46
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _