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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SCG2 All Species: 18.79
Human Site: Y457 Identified Species: 45.93
UniProt: P13521 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P13521 NP_003460.2 617 70941 Y457 T S Y F P N P Y N Q E K V L P
Chimpanzee Pan troglodytes XP_001166617 616 70758 Y456 T S Y F P N P Y N Q E K V L P
Rhesus Macaque Macaca mulatta XP_001108599 617 70905 Y457 T S Y F P N P Y N Q E K V L P
Dog Lupus familis XP_545669 615 70704 Y458 P P Y F S G Q Y N R E K L L P
Cat Felis silvestris
Mouse Mus musculus Q03517 617 70625 Y459 S P Y F P N Q Y S Q D K A L M
Rat Rattus norvegicus P10362 619 71013 Y459 S P Y F P N Q Y S R D K A L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511192 623 72014 L464 P A F F G K Q L S R E N V L P
Chicken Gallus gallus XP_422624 732 83316 L574 P S Y L L N R L N Q E N D L P
Frog Xenopus laevis NP_001081589 611 70741 N456 P A F L N Q F N Q N N G L Q R
Zebra Danio Brachydanio rerio NP_001071216 583 65903 G446 T N Y F N P N G R R G S L F L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 97.7 89.3 N.A. 81.6 80.7 N.A. 66.4 50.9 47.8 28 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.3 98.6 94.4 N.A. 90.4 89.6 N.A. 82.9 66.3 69.3 47 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 53.3 N.A. 53.3 46.6 N.A. 33.3 53.3 0 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 66.6 N.A. 73.3 73.3 N.A. 60 53.3 20 40 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 20 0 0 0 0 0 0 0 0 0 0 20 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 20 0 10 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 60 0 0 0 0 % E
% Phe: 0 0 20 80 0 0 10 0 0 0 0 0 0 10 0 % F
% Gly: 0 0 0 0 10 10 0 10 0 0 10 10 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 10 0 0 0 0 0 60 0 0 0 % K
% Leu: 0 0 0 20 10 0 0 20 0 0 0 0 30 80 20 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 10 0 0 20 60 10 10 50 10 10 20 0 0 0 % N
% Pro: 40 30 0 0 50 10 30 0 0 0 0 0 0 0 60 % P
% Gln: 0 0 0 0 0 10 40 0 10 50 0 0 0 10 0 % Q
% Arg: 0 0 0 0 0 0 10 0 10 40 0 0 0 0 10 % R
% Ser: 20 40 0 0 10 0 0 0 30 0 0 10 0 0 0 % S
% Thr: 40 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 40 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 80 0 0 0 0 60 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _