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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYH8 All Species: 18.18
Human Site: T882 Identified Species: 57.14
UniProt: P13535 Number Species: 7
    Phosphosite Substitution
    Charge Score: -0.29
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P13535 NP_002463.2 1937 222763 T882 E L E E K M V T L L K E K N D
Chimpanzee Pan troglodytes XP_511839 1937 222737 T882 E L E E K M V T L L K E K N D
Rhesus Macaque Macaca mulatta XP_001113700 1937 222504 T882 E L E E K M V T L L K E K N D
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P13542 1937 222689 T882 E L E E K M V T L L K E K N D
Rat Rattus norvegicus Q29RW1 1939 222861 A883 E L E E K M V A L M Q E K N D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P02565 1940 222798 S884 E L E E K M V S L L Q E K N D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P05661 1962 224447 K878 E L E A L N A K L L A E K T A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P02566 1966 225108 K891 E L E E S S A K L V E E K T S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 98.6 N.A. N.A. 97 91.1 N.A. N.A. 89.3 N.A. N.A. N.A. 54.5 N.A. 49.3 N.A.
Protein Similarity: 100 99.7 99.1 N.A. N.A. 98.5 96.5 N.A. N.A. 95.4 N.A. N.A. N.A. 72.8 N.A. 70 N.A.
P-Site Identity: 100 100 100 N.A. N.A. 100 80 N.A. N.A. 86.6 N.A. N.A. N.A. 46.6 N.A. 46.6 N.A.
P-Site Similarity: 100 100 100 N.A. N.A. 100 93.3 N.A. N.A. 100 N.A. N.A. N.A. 46.6 N.A. 60 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 13 0 0 25 13 0 0 13 0 0 0 13 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 75 % D
% Glu: 100 0 100 88 0 0 0 0 0 0 13 100 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 75 0 0 25 0 0 50 0 100 0 0 % K
% Leu: 0 100 0 0 13 0 0 0 100 75 0 0 0 0 0 % L
% Met: 0 0 0 0 0 75 0 0 0 13 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 13 0 0 0 0 0 0 0 75 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 25 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 13 13 0 13 0 0 0 0 0 0 13 % S
% Thr: 0 0 0 0 0 0 0 50 0 0 0 0 0 25 0 % T
% Val: 0 0 0 0 0 0 75 0 0 13 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _