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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP4B1
All Species:
16.06
Human Site:
S431
Identified Species:
39.26
UniProt:
P13584
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13584
NP_000770.2
511
58991
S431
V
F
D
S
L
R
F
S
T
E
N
A
S
K
R
Chimpanzee
Pan troglodytes
XP_513140
389
44979
T310
F
D
P
L
R
F
S
T
E
N
A
S
K
R
H
Rhesus Macaque
Macaca mulatta
XP_001108915
511
58897
S431
V
F
D
P
L
R
F
S
T
E
N
A
S
K
R
Dog
Lupus familis
XP_850244
511
59040
S431
V
F
D
P
L
R
F
S
S
E
N
V
A
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q64462
511
58882
S431
V
F
D
P
L
R
F
S
P
E
N
M
T
G
R
Rat
Rattus norvegicus
P15129
511
58918
S431
V
F
D
P
L
R
F
S
P
E
N
A
A
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519517
511
58983
V423
A
L
H
R
N
P
K
V
W
S
D
P
E
V
F
Chicken
Gallus gallus
XP_422455
504
57538
V416
G
I
H
R
N
R
D
V
W
E
D
P
E
V
F
Frog
Xenopus laevis
NP_001079027
515
59224
V427
C
I
H
R
N
P
S
V
W
K
D
P
E
V
F
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VA27
535
60739
V446
A
L
H
R
N
P
R
V
F
P
K
P
E
Q
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.9
96
86.8
N.A.
85.1
85.9
N.A.
71.2
53.8
56.1
N.A.
N.A.
32.1
N.A.
N.A.
N.A.
Protein Similarity:
100
75.1
96.8
92.7
N.A.
91.5
92.5
N.A.
82.1
70.2
73
N.A.
N.A.
51.7
N.A.
N.A.
N.A.
P-Site Identity:
100
0
93.3
66.6
N.A.
66.6
73.3
N.A.
0
13.3
0
N.A.
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
93.3
86.6
N.A.
73.3
80
N.A.
6.6
20
13.3
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
0
0
0
0
0
0
0
0
10
30
20
0
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
50
0
0
0
10
0
0
0
30
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
10
60
0
0
40
0
0
% E
% Phe:
10
50
0
0
0
10
50
0
10
0
0
0
0
0
40
% F
% Gly:
10
0
0
0
0
0
0
0
0
0
0
0
0
20
0
% G
% His:
0
0
40
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
10
0
0
10
10
0
10
20
0
% K
% Leu:
0
20
0
10
50
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
40
0
0
0
0
10
50
0
0
0
0
% N
% Pro:
0
0
10
40
0
30
0
0
20
10
0
40
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
0
0
0
40
10
60
10
0
0
0
0
0
0
20
50
% R
% Ser:
0
0
0
10
0
0
20
50
10
10
0
10
20
0
0
% S
% Thr:
0
0
0
0
0
0
0
10
20
0
0
0
10
0
0
% T
% Val:
50
0
0
0
0
0
0
40
0
0
0
10
0
30
0
% V
% Trp:
0
0
0
0
0
0
0
0
30
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _