KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP4B1
All Species:
28.79
Human Site:
Y153
Identified Species:
70.37
UniProt:
P13584
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13584
NP_000770.2
511
58991
Y153
H
Y
D
V
L
K
P
Y
V
A
V
F
T
E
S
Chimpanzee
Pan troglodytes
XP_513140
389
44979
T79
C
T
F
G
R
G
D
T
G
L
G
H
S
R
D
Rhesus Macaque
Macaca mulatta
XP_001108915
511
58897
Y153
H
Y
D
V
L
K
P
Y
V
A
L
F
A
E
S
Dog
Lupus familis
XP_850244
511
59040
Y153
H
Y
D
V
L
K
S
Y
V
A
V
F
T
N
S
Cat
Felis silvestris
Mouse
Mus musculus
Q64462
511
58882
Y153
H
Y
D
V
L
K
P
Y
V
A
I
F
A
E
S
Rat
Rattus norvegicus
P15129
511
58918
Y153
H
Y
D
V
L
K
P
Y
V
A
I
F
A
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519517
511
58983
Y158
H
Y
D
I
L
K
P
Y
I
R
V
F
V
D
S
Chicken
Gallus gallus
XP_422455
504
57538
Y155
H
Y
D
V
L
K
S
Y
V
S
L
M
S
D
S
Frog
Xenopus laevis
NP_001079027
515
59224
Y162
H
Y
D
V
L
K
P
Y
V
R
L
I
S
D
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VA27
535
60739
F170
H
F
K
I
L
D
D
F
I
D
V
F
N
E
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.9
96
86.8
N.A.
85.1
85.9
N.A.
71.2
53.8
56.1
N.A.
N.A.
32.1
N.A.
N.A.
N.A.
Protein Similarity:
100
75.1
96.8
92.7
N.A.
91.5
92.5
N.A.
82.1
70.2
73
N.A.
N.A.
51.7
N.A.
N.A.
N.A.
P-Site Identity:
100
0
86.6
86.6
N.A.
86.6
86.6
N.A.
66.6
60
66.6
N.A.
N.A.
33.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
93.3
86.6
N.A.
93.3
93.3
N.A.
86.6
86.6
86.6
N.A.
N.A.
60
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
50
0
0
30
0
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
80
0
0
10
20
0
0
10
0
0
0
30
10
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
50
0
% E
% Phe:
0
10
10
0
0
0
0
10
0
0
0
70
0
0
0
% F
% Gly:
0
0
0
10
0
10
0
0
10
0
10
0
0
0
0
% G
% His:
90
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
0
0
20
0
0
0
0
20
0
20
10
0
0
0
% I
% Lys:
0
0
10
0
0
80
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
90
0
0
0
0
10
30
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% N
% Pro:
0
0
0
0
0
0
60
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
0
0
10
0
0
0
0
20
0
0
0
10
0
% R
% Ser:
0
0
0
0
0
0
20
0
0
10
0
0
30
0
80
% S
% Thr:
0
10
0
0
0
0
0
10
0
0
0
0
20
0
0
% T
% Val:
0
0
0
70
0
0
0
0
70
0
40
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
80
0
0
0
0
0
80
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _