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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITGA4
All Species:
25.45
Human Site:
S1021
Identified Species:
46.67
UniProt:
P13612
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13612
NP_000876.3
1032
114872
S1021
Q
E
E
N
R
R
D
S
W
S
Y
I
N
S
K
Chimpanzee
Pan troglodytes
XP_525977
1032
114817
S1021
Q
E
E
N
R
R
D
S
W
S
Y
I
N
S
K
Rhesus Macaque
Macaca mulatta
XP_001100929
1032
114958
S1021
Q
E
E
N
R
R
D
S
W
S
Y
I
N
S
K
Dog
Lupus familis
XP_545551
1165
128321
S1153
Q
E
E
N
R
R
D
S
W
S
Y
V
N
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q00651
1039
115677
S1028
Q
E
E
N
R
R
D
S
W
S
Y
V
N
S
K
Rat
Rattus norvegicus
Q63258
1135
124176
L1082
Q
Y
H
A
V
K
I
L
R
E
D
R
Q
Q
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515892
940
104353
S930
Q
D
E
D
R
R
E
S
W
S
Y
V
D
S
C
Chicken
Gallus gallus
P26008
1034
114370
Q1023
E
Q
E
R
E
Q
L
Q
P
H
E
N
G
E
G
Frog
Xenopus laevis
Q91687
1032
115197
E1019
T
E
E
T
S
R
R
E
S
W
N
Y
L
N
K
Zebra Danio
Brachydanio rerio
XP_002663459
1018
113210
S1007
K
E
K
F
R
R
D
S
W
D
Y
V
P
K
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24247
1146
127955
K1128
T
L
S
G
N
L
E
K
M
N
E
E
K
P
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34446
1226
135921
R1198
H
A
E
L
R
A
D
R
Q
P
N
A
Q
Y
A
Sea Urchin
Strong. purpuratus
XP_794080
1226
134761
Q1209
S
Q
A
P
N
Q
P
Q
M
Q
A
P
G
A
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97
75.1
N.A.
84.1
25.8
N.A.
65.5
26.2
54.4
47.6
N.A.
24
N.A.
22.1
24.7
Protein Similarity:
100
99.9
98.4
81.7
N.A.
91.8
44.4
N.A.
77.5
46.6
74.1
65.3
N.A.
43.4
N.A.
41.3
42.9
P-Site Identity:
100
100
100
93.3
N.A.
93.3
6.6
N.A.
60
6.6
26.6
46.6
N.A.
0
N.A.
20
0
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
93.3
26.6
33.3
66.6
N.A.
13.3
N.A.
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
8
0
8
0
0
0
0
8
8
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
8
0
8
0
0
54
0
0
8
8
0
8
0
0
% D
% Glu:
8
54
70
0
8
0
16
8
0
8
16
8
0
8
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
16
% F
% Gly:
0
0
0
8
0
0
0
0
0
0
0
0
16
0
8
% G
% His:
8
0
8
0
0
0
0
0
0
8
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
0
24
0
0
0
% I
% Lys:
8
0
8
0
0
8
0
8
0
0
0
0
8
8
47
% K
% Leu:
0
8
0
8
0
8
8
8
0
0
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
16
0
0
0
0
0
0
% M
% Asn:
0
0
0
39
16
0
0
0
0
8
16
8
39
8
0
% N
% Pro:
0
0
0
8
0
0
8
0
8
8
0
8
8
8
0
% P
% Gln:
54
16
0
0
0
16
0
16
8
8
0
0
16
8
8
% Q
% Arg:
0
0
0
8
62
62
8
8
8
0
0
8
0
0
0
% R
% Ser:
8
0
8
0
8
0
0
54
8
47
0
0
0
47
0
% S
% Thr:
16
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
8
0
0
0
0
0
0
31
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
54
8
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
54
8
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _