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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITGA4
All Species:
19.04
Human Site:
S1029
Identified Species:
34.91
UniProt:
P13612
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13612
NP_000876.3
1032
114872
S1029
W
S
Y
I
N
S
K
S
N
D
D
_
_
_
_
Chimpanzee
Pan troglodytes
XP_525977
1032
114817
S1029
W
S
Y
I
N
S
K
S
N
D
D
_
_
_
_
Rhesus Macaque
Macaca mulatta
XP_001100929
1032
114958
S1029
W
S
Y
I
N
S
K
S
N
D
D
_
_
_
_
Dog
Lupus familis
XP_545551
1165
128321
S1161
W
S
Y
V
N
S
K
S
N
D
D
D
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q00651
1039
115677
S1036
W
S
Y
V
N
S
K
S
N
D
D
_
_
_
_
Rat
Rattus norvegicus
Q63258
1135
124176
K1090
R
E
D
R
Q
Q
F
K
E
E
K
T
G
T
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515892
940
104353
Chicken
Gallus gallus
P26008
1034
114370
T1031
P
H
E
N
G
E
G
T
S
E
A
_
_
_
_
Frog
Xenopus laevis
Q91687
1032
115197
D1027
S
W
N
Y
L
N
K
D
E
K
E
V
K
_
_
Zebra Danio
Brachydanio rerio
XP_002663459
1018
113210
E1015
W
D
Y
V
P
K
H
E
S
V
S
_
_
_
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24247
1146
127955
L1136
M
N
E
E
K
P
F
L
A
P
S
K
N
T
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34446
1226
135921
D1206
Q
P
N
A
Q
Y
A
D
S
Q
S
R
Y
T
S
Sea Urchin
Strong. purpuratus
XP_794080
1226
134761
R1217
M
Q
A
P
G
A
Q
R
G
P
M
G
Q
L
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97
75.1
N.A.
84.1
25.8
N.A.
65.5
26.2
54.4
47.6
N.A.
24
N.A.
22.1
24.7
Protein Similarity:
100
99.9
98.4
81.7
N.A.
91.8
44.4
N.A.
77.5
46.6
74.1
65.3
N.A.
43.4
N.A.
41.3
42.9
P-Site Identity:
100
100
100
83.3
N.A.
90.9
0
N.A.
0
0
7.6
18.1
N.A.
0
N.A.
0
0
P-Site Similarity:
100
100
100
91.6
N.A.
100
20
N.A.
0
27.2
23
36.3
N.A.
6.6
N.A.
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
0
8
8
0
8
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
0
0
0
0
16
0
39
39
8
0
0
0
% D
% Glu:
0
8
16
8
0
8
0
8
16
16
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
16
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
16
0
8
0
8
0
0
8
8
0
0
% G
% His:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
24
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
0
0
0
8
8
47
8
0
8
8
8
8
0
0
% K
% Leu:
0
0
0
0
8
0
0
8
0
0
0
0
0
8
0
% L
% Met:
16
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
8
16
8
39
8
0
0
39
0
0
0
8
0
0
% N
% Pro:
8
8
0
8
8
8
0
0
0
16
0
0
0
0
0
% P
% Gln:
8
8
0
0
16
8
8
0
0
8
0
0
8
0
0
% Q
% Arg:
8
0
0
8
0
0
0
8
0
0
0
8
0
0
8
% R
% Ser:
8
39
0
0
0
39
0
39
24
0
24
0
0
0
8
% S
% Thr:
0
0
0
0
0
0
0
8
0
0
0
8
0
24
0
% T
% Val:
0
0
0
24
0
0
0
0
0
8
0
8
0
0
0
% V
% Trp:
47
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
47
8
0
8
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
47
54
62
62
% _