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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EEF2
All Species:
31.52
Human Site:
T177
Identified Species:
53.33
UniProt:
P13639
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13639
NP_001952.1
858
95338
T177
E
P
E
E
L
Y
Q
T
F
Q
R
I
V
E
N
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001118006
1434
155458
T753
E
P
E
E
L
Y
Q
T
F
Q
R
I
V
E
N
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P58252
858
95296
T177
E
P
E
E
L
Y
Q
T
F
Q
R
I
V
E
N
Rat
Rattus norvegicus
P05197
858
95265
T177
E
P
E
E
L
Y
Q
T
F
Q
R
I
V
E
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515708
919
102141
T238
E
P
E
E
L
Y
Q
T
F
Q
R
I
V
E
N
Chicken
Gallus gallus
Q90705
858
95360
T177
D
P
E
E
L
Y
Q
T
F
Q
R
I
V
E
N
Frog
Xenopus laevis
NP_001080656
858
95409
T177
E
P
E
A
L
Y
Q
T
F
Q
R
I
V
E
N
Zebra Danio
Brachydanio rerio
XP_697966
861
95866
T177
E
P
D
E
L
F
Q
T
F
Q
R
I
V
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13060
844
94440
Q180
L
D
A
E
E
L
Y
Q
T
F
Q
R
I
V
E
Honey Bee
Apis mellifera
XP_392691
844
94564
Q180
L
D
S
E
D
L
Y
Q
T
F
Q
R
I
V
E
Nematode Worm
Caenorhab. elegans
P29691
852
94778
Q188
L
G
A
E
E
L
F
Q
T
F
Q
R
I
V
E
Sea Urchin
Strong. purpuratus
XP_001178871
842
94328
Q178
L
E
M
E
D
L
Y
Q
T
F
Q
R
I
V
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32324
842
93271
L174
L
Q
V
S
K
E
D
L
Y
Q
T
F
A
R
T
Red Bread Mold
Neurospora crassa
Q96X45
844
93243
L176
L
Q
V
S
K
E
D
L
Y
Q
S
F
S
R
T
Conservation
Percent
Protein Identity:
100
N.A.
59.7
N.A.
N.A.
99
99.1
N.A.
92.3
97.3
95.2
92.4
N.A.
78.7
80.6
80.1
75.7
Protein Similarity:
100
N.A.
59.8
N.A.
N.A.
99.5
99.6
N.A.
92.8
98.5
98.2
97.3
N.A.
86.9
87.7
88.6
85.9
P-Site Identity:
100
N.A.
100
N.A.
N.A.
100
100
N.A.
100
93.3
93.3
86.6
N.A.
6.6
6.6
6.6
6.6
P-Site Similarity:
100
N.A.
100
N.A.
N.A.
100
100
N.A.
100
100
93.3
100
N.A.
20
20
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
66.4
67.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
78.7
80.8
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
15
8
0
0
0
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
15
8
0
15
0
15
0
0
0
0
0
0
0
0
% D
% Glu:
50
8
50
79
15
15
0
0
0
0
0
0
0
58
29
% E
% Phe:
0
0
0
0
0
8
8
0
58
29
0
15
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
58
29
0
0
% I
% Lys:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
43
0
0
0
58
29
0
15
0
0
0
0
0
0
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
58
% N
% Pro:
0
58
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
15
0
0
0
0
58
29
0
72
29
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
58
29
0
15
0
% R
% Ser:
0
0
8
15
0
0
0
0
0
0
8
0
8
0
0
% S
% Thr:
0
0
0
0
0
0
0
58
29
0
8
0
0
0
15
% T
% Val:
0
0
15
0
0
0
0
0
0
0
0
0
58
29
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
50
22
0
15
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _