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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KRT10 All Species: 9.7
Human Site: S143 Identified Species: 26.67
UniProt: P13645 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P13645 NP_000412.3 584 58827 S143 G G D G G L L S G N E K V T M
Chimpanzee Pan troglodytes A5A6N2 450 49288 G26 G S L R L S G G G T S F G T G
Rhesus Macaque Macaca mulatta XP_001100571 610 62082 S132 G G D G G L L S G N E K V T M
Dog Lupus familis XP_850106 502 54677 S76 A G S N A C G S S F A G S G F
Cat Felis silvestris
Mouse Mus musculus P02535 570 57751 S141 G D G G S L L S G N G R V T M
Rat Rattus norvegicus Q6IFW6 526 56487 G83 G S F G G G Y G G G S F G G G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520537 539 56339 C115 G S F G G G S C G G G G F G G
Chicken Gallus gallus Q6PVZ1 467 50967 S41 A P S V H G G S S S Y S V S S
Frog Xenopus laevis P05781 419 45634
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 46.5 87.8 47.2 N.A. 82.7 71.5 N.A. 69.5 46.7 46.7 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 55.9 90.4 58.3 N.A. 86.8 77.9 N.A. 76.3 58.3 56.5 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 20 100 13.3 N.A. 66.6 26.6 N.A. 26.6 13.3 0 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 100 13.3 N.A. 73.3 26.6 N.A. 26.6 26.6 0 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 23 0 0 0 12 0 0 0 0 0 12 0 0 0 0 % A
% Cys: 0 0 0 0 0 12 0 12 0 0 0 0 0 0 0 % C
% Asp: 0 12 23 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 23 0 0 0 0 % E
% Phe: 0 0 23 0 0 0 0 0 0 12 0 23 12 0 12 % F
% Gly: 67 34 12 56 45 34 34 23 67 23 23 23 23 34 34 % G
% His: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 23 0 0 0 % K
% Leu: 0 0 12 0 12 34 34 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 34 % M
% Asn: 0 0 0 12 0 0 0 0 0 34 0 0 0 0 0 % N
% Pro: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 12 0 0 0 0 0 0 0 12 0 0 0 % R
% Ser: 0 34 23 0 12 12 12 56 23 12 23 12 12 12 12 % S
% Thr: 0 0 0 0 0 0 0 0 0 12 0 0 0 45 0 % T
% Val: 0 0 0 12 0 0 0 0 0 0 0 0 45 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 12 0 0 0 12 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _