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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KRT10
All Species:
6.67
Human Site:
Y449
Identified Species:
18.33
UniProt:
P13645
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13645
NP_000412.3
584
58827
Y449
L
E
N
E
I
Q
T
Y
R
S
L
L
E
G
E
Chimpanzee
Pan troglodytes
A5A6N2
450
49288
L316
L
E
I
E
L
Q
S
L
L
A
T
K
H
S
L
Rhesus Macaque
Macaca mulatta
XP_001100571
610
62082
Y438
L
E
N
E
I
Q
T
Y
R
S
L
L
E
G
E
Dog
Lupus familis
XP_850106
502
54677
L368
V
L
A
T
K
H
S
L
E
C
S
L
T
E
T
Cat
Felis silvestris
Mouse
Mus musculus
P02535
570
57751
I436
E
Y
Q
Q
L
L
D
I
K
T
R
L
E
N
E
Rat
Rattus norvegicus
Q6IFW6
526
56487
S391
L
K
Q
S
L
E
A
S
L
A
E
T
E
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520537
539
56339
E405
Q
V
Q
I
T
S
L
E
E
Q
L
Q
Q
I
R
Chicken
Gallus gallus
Q6PVZ1
467
50967
Q333
T
E
L
R
R
T
I
Q
S
L
E
I
D
L
Q
Frog
Xenopus laevis
P05781
419
45634
K285
N
Q
K
S
G
E
L
K
K
E
I
Q
T
G
V
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.5
87.8
47.2
N.A.
82.7
71.5
N.A.
69.5
46.7
46.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
55.9
90.4
58.3
N.A.
86.8
77.9
N.A.
76.3
58.3
56.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
26.6
100
6.6
N.A.
20
20
N.A.
6.6
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
46.6
100
20
N.A.
46.6
46.6
N.A.
13.3
26.6
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
0
0
12
0
0
23
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
12
0
0
0
0
0
12
0
0
% D
% Glu:
12
45
0
34
0
23
0
12
23
12
23
0
45
12
34
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
12
0
0
0
0
0
0
0
0
45
0
% G
% His:
0
0
0
0
0
12
0
0
0
0
0
0
12
0
0
% H
% Ile:
0
0
12
12
23
0
12
12
0
0
12
12
0
12
0
% I
% Lys:
0
12
12
0
12
0
0
12
23
0
0
12
0
0
0
% K
% Leu:
45
12
12
0
34
12
23
23
23
12
34
45
0
12
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
23
0
0
0
0
0
0
0
0
0
0
12
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
12
12
34
12
0
34
0
12
0
12
0
23
12
0
12
% Q
% Arg:
0
0
0
12
12
0
0
0
23
0
12
0
0
0
23
% R
% Ser:
0
0
0
23
0
12
23
12
12
23
12
0
0
12
0
% S
% Thr:
12
0
0
12
12
12
23
0
0
12
12
12
23
0
12
% T
% Val:
12
12
0
0
0
0
0
0
0
0
0
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
12
0
0
0
0
0
23
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _