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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDIA4
All Species:
20.91
Human Site:
S126
Identified Species:
32.86
UniProt:
P13667
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13667
NP_004902.1
645
72932
S126
K
I
D
A
T
S
A
S
V
L
A
S
R
F
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_539831
628
70318
T120
P
V
A
K
I
D
A
T
S
E
S
A
L
A
G
Cat
Felis silvestris
Mouse
Mus musculus
P08003
638
71955
S119
K
I
D
A
T
S
A
S
M
L
A
S
K
F
D
Rat
Rattus norvegicus
P38659
643
72702
S124
K
I
D
A
T
S
A
S
M
L
A
S
K
F
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q8JG64
505
56163
R8
M
S
V
P
R
P
S
R
A
A
L
L
L
L
V
Frog
Xenopus laevis
NP_001088331
637
71736
T119
K
I
D
A
T
V
A
T
N
I
A
G
R
Y
D
Zebra Danio
Brachydanio rerio
NP_956073
645
72696
S126
K
V
D
A
T
K
A
S
G
L
G
S
R
F
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
Honey Bee
Apis mellifera
XP_623282
490
55838
Nematode Worm
Caenorhab. elegans
P34329
618
69779
T95
K
V
D
A
T
V
E
T
E
L
G
K
R
F
E
Sea Urchin
Strong. purpuratus
XP_791396
637
72173
K115
K
V
D
A
T
E
N
K
E
L
A
S
R
F
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P52588
513
57078
L15
W
I
S
L
L
L
A
L
A
V
A
L
S
A
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SRG3
508
56346
I11
K
G
F
A
C
F
S
I
L
L
L
L
S
L
F
Baker's Yeast
Sacchar. cerevisiae
P17967
522
58209
E25
S
S
V
F
A
Q
Q
E
A
V
A
P
E
D
S
Red Bread Mold
Neurospora crassa
Q92249
369
39263
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
81.7
N.A.
87.7
88
N.A.
N.A.
32.8
72
72.2
N.A.
30.2
30.8
47.4
53.1
Protein Similarity:
100
N.A.
N.A.
89.1
N.A.
93.6
94.2
N.A.
N.A.
47.4
84.6
84.8
N.A.
47.5
47.4
63
68.9
P-Site Identity:
100
N.A.
N.A.
6.6
N.A.
86.6
86.6
N.A.
N.A.
0
60
66.6
N.A.
0
0
46.6
66.6
P-Site Similarity:
100
N.A.
N.A.
33.3
N.A.
100
100
N.A.
N.A.
6.6
80
80
N.A.
0
0
66.6
73.3
Percent
Protein Identity:
N.A.
29.6
N.A.
30.3
23.5
22.3
Protein Similarity:
N.A.
44.5
N.A.
48.5
37.5
34.8
P-Site Identity:
N.A.
20
N.A.
20
6.6
0
P-Site Similarity:
N.A.
26.6
N.A.
33.3
13.3
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
54
7
0
47
0
20
7
47
7
0
14
0
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
47
0
0
7
0
0
0
0
0
0
0
7
34
% D
% Glu:
0
0
0
0
0
7
7
7
14
7
0
0
7
0
14
% E
% Phe:
0
0
7
7
0
7
0
0
0
0
0
0
0
40
7
% F
% Gly:
0
7
0
0
0
0
0
0
7
0
14
7
0
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
34
0
0
7
0
0
7
0
7
0
0
0
0
0
% I
% Lys:
54
0
0
7
0
7
0
7
0
0
0
7
14
0
0
% K
% Leu:
0
0
0
7
7
7
0
7
7
47
14
20
14
14
0
% L
% Met:
7
0
0
0
0
0
0
0
14
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
7
0
7
0
0
0
0
0
0
% N
% Pro:
7
0
0
7
0
7
0
0
0
0
0
7
0
0
0
% P
% Gln:
0
0
0
0
0
7
7
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
7
0
0
7
0
0
0
0
34
0
7
% R
% Ser:
7
14
7
0
0
20
14
27
7
0
7
34
14
0
7
% S
% Thr:
0
0
0
0
47
0
0
20
0
0
0
0
0
0
0
% T
% Val:
0
27
14
0
0
14
0
0
7
14
0
0
0
0
7
% V
% Trp:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _