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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDIA4
All Species:
19.09
Human Site:
S287
Identified Species:
30
UniProt:
P13667
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13667
NP_004902.1
645
72932
S287
I
E
Q
S
G
P
P
S
K
E
I
L
T
L
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_539831
628
70318
E278
G
I
V
D
Y
M
I
E
Q
S
G
P
P
S
K
Cat
Felis silvestris
Mouse
Mus musculus
P08003
638
71955
S280
I
E
Q
S
G
P
P
S
K
E
I
L
T
L
K
Rat
Rattus norvegicus
P38659
643
72702
S285
V
E
Q
S
G
P
P
S
K
E
I
L
T
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q8JG64
505
56163
A165
F
R
D
A
S
G
D
A
Y
S
E
F
M
K
A
Frog
Xenopus laevis
NP_001088331
637
71736
S280
T
E
Q
A
G
P
P
S
K
Q
I
Q
A
V
K
Zebra Danio
Brachydanio rerio
NP_956073
645
72696
S287
S
D
Q
A
G
P
P
S
K
Q
V
Q
T
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
A156
F
L
K
D
N
E
I
A
I
I
G
F
F
K
D
Honey Bee
Apis mellifera
XP_623282
490
55838
E150
K
S
F
L
D
S
D
E
V
S
V
V
G
F
F
Nematode Worm
Caenorhab. elegans
P34329
618
69779
A257
T
D
Q
S
K
P
A
A
K
K
L
P
K
L
K
Sea Urchin
Strong. purpuratus
XP_791396
637
72173
S276
Q
K
Q
V
G
D
S
S
Q
L
L
G
S
T
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P52588
513
57078
F172
K
I
Y
I
V
G
I
F
A
E
F
S
G
T
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SRG3
508
56346
P168
V
V
A
V
G
V
F
P
K
L
S
G
D
E
F
Baker's Yeast
Sacchar. cerevisiae
P17967
522
58209
N182
A
T
F
Y
S
M
A
N
K
H
F
N
D
Y
D
Red Bread Mold
Neurospora crassa
Q92249
369
39263
N29
V
L
D
L
I
P
S
N
F
D
D
V
V
L
K
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
81.7
N.A.
87.7
88
N.A.
N.A.
32.8
72
72.2
N.A.
30.2
30.8
47.4
53.1
Protein Similarity:
100
N.A.
N.A.
89.1
N.A.
93.6
94.2
N.A.
N.A.
47.4
84.6
84.8
N.A.
47.5
47.4
63
68.9
P-Site Identity:
100
N.A.
N.A.
6.6
N.A.
100
93.3
N.A.
N.A.
0
60
60
N.A.
0
0
40
26.6
P-Site Similarity:
100
N.A.
N.A.
13.3
N.A.
100
100
N.A.
N.A.
13.3
80
86.6
N.A.
13.3
13.3
66.6
53.3
Percent
Protein Identity:
N.A.
29.6
N.A.
30.3
23.5
22.3
Protein Similarity:
N.A.
44.5
N.A.
48.5
37.5
34.8
P-Site Identity:
N.A.
6.6
N.A.
13.3
6.6
20
P-Site Similarity:
N.A.
13.3
N.A.
20
13.3
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
20
0
0
14
20
7
0
0
0
7
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
14
14
14
7
7
14
0
0
7
7
0
14
0
14
% D
% Glu:
0
27
0
0
0
7
0
14
0
27
7
0
0
7
7
% E
% Phe:
14
0
14
0
0
0
7
7
7
0
14
14
7
7
14
% F
% Gly:
7
0
0
0
47
14
0
0
0
0
14
14
14
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% H
% Ile:
14
14
0
7
7
0
20
0
7
7
27
0
0
0
0
% I
% Lys:
14
7
7
0
7
0
0
0
54
7
0
0
7
14
60
% K
% Leu:
0
14
0
14
0
0
0
0
0
14
14
20
0
40
0
% L
% Met:
0
0
0
0
0
14
0
0
0
0
0
0
7
0
0
% M
% Asn:
0
0
0
0
7
0
0
14
0
0
0
7
0
0
0
% N
% Pro:
0
0
0
0
0
47
34
7
0
0
0
14
7
0
0
% P
% Gln:
7
0
47
0
0
0
0
0
14
14
0
14
0
0
0
% Q
% Arg:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
7
7
0
27
14
7
14
40
0
20
7
7
7
7
0
% S
% Thr:
14
7
0
0
0
0
0
0
0
0
0
0
27
14
0
% T
% Val:
20
7
7
14
7
7
0
0
7
0
14
14
7
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
7
7
0
0
0
7
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _