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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDIA4
All Species:
17.58
Human Site:
S403
Identified Species:
27.62
UniProt:
P13667
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13667
NP_004902.1
645
72932
S403
L
V
G
H
R
K
V
S
N
D
A
K
R
Y
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_539831
628
70318
G386
P
R
A
V
G
L
Q
G
V
R
P
A
L
P
L
Cat
Felis silvestris
Mouse
Mus musculus
P08003
638
71955
S396
L
V
G
H
R
K
T
S
N
D
A
K
R
Y
S
Rat
Rattus norvegicus
P38659
643
72702
S401
L
V
G
H
R
K
T
S
N
D
A
K
R
Y
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q8JG64
505
56163
K272
V
D
Y
E
K
N
A
K
G
S
N
Y
W
R
N
Frog
Xenopus laevis
NP_001088331
637
71736
S396
L
V
G
H
R
K
S
S
N
E
A
K
R
Y
S
Zebra Danio
Brachydanio rerio
NP_956073
645
72696
S403
L
V
G
H
R
R
Q
S
N
D
A
K
R
Y
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
R263
H
L
L
F
F
V
S
R
E
G
G
H
I
E
K
Honey Bee
Apis mellifera
XP_623282
490
55838
Y257
N
P
L
V
V
A
Y
Y
A
V
D
Y
I
K
N
Nematode Worm
Caenorhab. elegans
P34329
618
69779
K372
L
V
G
K
M
T
K
K
N
A
A
T
R
Y
T
Sea Urchin
Strong. purpuratus
XP_791396
637
72173
E391
L
V
G
Q
M
T
K
E
N
R
E
R
R
Y
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P52588
513
57078
N279
P
K
A
M
L
F
L
N
F
S
T
G
P
F
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SRG3
508
56346
T275
A
M
M
F
V
N
F
T
G
A
T
A
E
A
L
Baker's Yeast
Sacchar. cerevisiae
P17967
522
58209
N289
K
K
N
R
G
L
M
N
F
V
S
I
D
A
R
Red Bread Mold
Neurospora crassa
Q92249
369
39263
K136
T
G
V
K
A
R
K
K
G
S
A
P
S
L
V
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
81.7
N.A.
87.7
88
N.A.
N.A.
32.8
72
72.2
N.A.
30.2
30.8
47.4
53.1
Protein Similarity:
100
N.A.
N.A.
89.1
N.A.
93.6
94.2
N.A.
N.A.
47.4
84.6
84.8
N.A.
47.5
47.4
63
68.9
P-Site Identity:
100
N.A.
N.A.
0
N.A.
86.6
86.6
N.A.
N.A.
0
80
86.6
N.A.
0
0
53.3
46.6
P-Site Similarity:
100
N.A.
N.A.
0
N.A.
93.3
93.3
N.A.
N.A.
13.3
93.3
93.3
N.A.
6.6
0
53.3
53.3
Percent
Protein Identity:
N.A.
29.6
N.A.
30.3
23.5
22.3
Protein Similarity:
N.A.
44.5
N.A.
48.5
37.5
34.8
P-Site Identity:
N.A.
0
N.A.
0
0
6.6
P-Site Similarity:
N.A.
20
N.A.
13.3
20
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
14
0
7
7
7
0
7
14
47
14
0
14
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
0
0
0
0
0
27
7
0
7
0
7
% D
% Glu:
0
0
0
7
0
0
0
7
7
7
7
0
7
7
0
% E
% Phe:
0
0
0
14
7
7
7
0
14
0
0
0
0
7
0
% F
% Gly:
0
7
47
0
14
0
0
7
20
7
7
7
0
0
0
% G
% His:
7
0
0
34
0
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
7
14
0
0
% I
% Lys:
7
14
0
14
7
27
20
20
0
0
0
34
0
7
7
% K
% Leu:
47
7
14
0
7
14
7
0
0
0
0
0
7
7
14
% L
% Met:
0
7
7
7
14
0
7
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
7
0
0
14
0
14
47
0
7
0
0
0
14
% N
% Pro:
14
7
0
0
0
0
0
0
0
0
7
7
7
7
0
% P
% Gln:
0
0
0
7
0
0
14
0
0
0
0
0
0
0
0
% Q
% Arg:
0
7
0
7
34
14
0
7
0
14
0
7
47
7
7
% R
% Ser:
0
0
0
0
0
0
14
34
0
20
7
0
7
0
20
% S
% Thr:
7
0
0
0
0
14
14
7
0
0
14
7
0
0
27
% T
% Val:
7
47
7
14
14
7
7
0
7
14
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% W
% Tyr:
0
0
7
0
0
0
7
7
0
0
0
14
0
47
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _