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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDIA4
All Species:
16.97
Human Site:
S495
Identified Species:
26.67
UniProt:
P13667
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13667
NP_004902.1
645
72932
S495
M
E
P
E
E
F
D
S
D
T
L
R
E
F
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_539831
628
70318
A478
M
E
P
D
D
F
D
A
D
A
L
R
E
F
V
Cat
Felis silvestris
Mouse
Mus musculus
P08003
638
71955
S488
M
E
P
E
E
F
D
S
D
T
L
R
E
F
V
Rat
Rattus norvegicus
P38659
643
72702
S493
M
E
P
E
E
F
D
S
D
A
L
Q
E
F
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q8JG64
505
56163
K364
G
N
L
K
K
Y
L
K
S
E
P
V
P
E
N
Frog
Xenopus laevis
NP_001088331
637
71736
S488
K
E
P
E
E
L
D
S
D
G
L
R
D
F
V
Zebra Danio
Brachydanio rerio
NP_956073
645
72696
S495
M
E
P
E
E
F
D
S
D
V
L
R
S
F
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
L355
D
G
K
L
K
Q
H
L
L
S
Q
E
L
P
E
Honey Bee
Apis mellifera
XP_623282
490
55838
P349
M
E
A
G
V
L
E
P
Y
L
K
S
E
P
I
Nematode Worm
Caenorhab. elegans
P34329
618
69779
F464
Y
P
M
N
P
D
E
F
D
G
E
L
D
E
N
Sea Urchin
Strong. purpuratus
XP_791396
637
72173
D483
F
K
L
E
P
E
D
D
F
E
S
D
V
L
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P52588
513
57078
P371
T
P
F
R
N
S
E
P
I
P
E
V
N
N
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SRG3
508
56346
P367
H
K
K
S
Q
P
I
P
A
E
N
N
E
P
V
Baker's Yeast
Sacchar. cerevisiae
P17967
522
58209
L381
Q
D
S
S
V
F
Q
L
V
G
K
N
H
D
E
Red Bread Mold
Neurospora crassa
Q92249
369
39263
T228
K
F
F
P
K
G
S
T
T
P
E
D
Y
N
G
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
81.7
N.A.
87.7
88
N.A.
N.A.
32.8
72
72.2
N.A.
30.2
30.8
47.4
53.1
Protein Similarity:
100
N.A.
N.A.
89.1
N.A.
93.6
94.2
N.A.
N.A.
47.4
84.6
84.8
N.A.
47.5
47.4
63
68.9
P-Site Identity:
100
N.A.
N.A.
73.3
N.A.
100
86.6
N.A.
N.A.
0
73.3
86.6
N.A.
0
20
6.6
13.3
P-Site Similarity:
100
N.A.
N.A.
93.3
N.A.
100
93.3
N.A.
N.A.
20
80
86.6
N.A.
13.3
33.3
20
20
Percent
Protein Identity:
N.A.
29.6
N.A.
30.3
23.5
22.3
Protein Similarity:
N.A.
44.5
N.A.
48.5
37.5
34.8
P-Site Identity:
N.A.
0
N.A.
13.3
6.6
0
P-Site Similarity:
N.A.
6.6
N.A.
26.6
13.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
0
0
7
7
14
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
0
7
7
7
47
7
47
0
0
14
14
7
0
% D
% Glu:
0
47
0
40
34
7
20
0
0
20
20
7
40
14
20
% E
% Phe:
7
7
14
0
0
40
0
7
7
0
0
0
0
40
0
% F
% Gly:
7
7
0
7
0
7
0
0
0
20
0
0
0
0
7
% G
% His:
7
0
0
0
0
0
7
0
0
0
0
0
7
0
0
% H
% Ile:
0
0
0
0
0
0
7
0
7
0
0
0
0
0
7
% I
% Lys:
14
14
14
7
20
0
0
7
0
0
14
0
0
0
0
% K
% Leu:
0
0
14
7
0
14
7
14
7
7
40
7
7
7
0
% L
% Met:
40
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
7
7
0
0
0
0
0
7
14
7
14
14
% N
% Pro:
0
14
40
7
14
7
0
20
0
14
7
0
7
20
0
% P
% Gln:
7
0
0
0
7
7
7
0
0
0
7
7
0
0
0
% Q
% Arg:
0
0
0
7
0
0
0
0
0
0
0
34
0
0
7
% R
% Ser:
0
0
7
14
0
7
7
34
7
7
7
7
7
0
0
% S
% Thr:
7
0
0
0
0
0
0
7
7
14
0
0
0
0
0
% T
% Val:
0
0
0
0
14
0
0
0
7
7
0
14
7
0
47
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
7
0
0
7
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _