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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDIA4 All Species: 11.82
Human Site: S567 Identified Species: 18.57
UniProt: P13667 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P13667 NP_004902.1 645 72932 S567 Q L E P V Y N S L A K K Y K G
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_539831 628 70318 A550 Q L E P E Y A A L G K K Y K N
Cat Felis silvestris
Mouse Mus musculus P08003 638 71955 S560 Q L E P I Y T S L G K K Y K G
Rat Rattus norvegicus P38659 643 72702 S565 Q L E P V Y T S L G K K Y K G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q8JG64 505 56163 D433 N I V I A K M D A T A N D V P
Frog Xenopus laevis NP_001088331 637 71736 D560 S L E P I Y N D L G K K Y R S
Zebra Danio Brachydanio rerio NP_956073 645 72696 S567 K L E P D Y I S L G K K Y K N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54399 496 55763 K424 N E D I V I A K M D S T A N E
Honey Bee Apis mellifera XP_623282 490 55838 K418 N E D V E I I K F D A T A N D
Nematode Worm Caenorhab. elegans P34329 618 69779 E541 S F E S K Y V E L A Q A L K K
Sea Urchin Strong. purpuratus XP_791396 637 72173 K558 K L D P V Y K K L G K K F A N
Poplar Tree Populus trichocarpa
Maize Zea mays P52588 513 57078 N441 A K M D A T A N D V P S E F D
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SRG3 508 56346 D436 K L D A T A N D I P S D T F D
Baker's Yeast Sacchar. cerevisiae P17967 522 58209 Y450 R G V V I E G Y P T I V L Y P
Red Bread Mold Neurospora crassa Q92249 369 39263 L297 A K E A V K S L K N S A E L K
Conservation
Percent
Protein Identity: 100 N.A. N.A. 81.7 N.A. 87.7 88 N.A. N.A. 32.8 72 72.2 N.A. 30.2 30.8 47.4 53.1
Protein Similarity: 100 N.A. N.A. 89.1 N.A. 93.6 94.2 N.A. N.A. 47.4 84.6 84.8 N.A. 47.5 47.4 63 68.9
P-Site Identity: 100 N.A. N.A. 66.6 N.A. 80 86.6 N.A. N.A. 0 60 66.6 N.A. 6.6 0 33.3 46.6
P-Site Similarity: 100 N.A. N.A. 73.3 N.A. 86.6 86.6 N.A. N.A. 6.6 73.3 73.3 N.A. 20 6.6 40 66.6
Percent
Protein Identity: N.A. 29.6 N.A. 30.3 23.5 22.3
Protein Similarity: N.A. 44.5 N.A. 48.5 37.5 34.8
P-Site Identity: N.A. 0 N.A. 13.3 0 13.3
P-Site Similarity: N.A. 6.6 N.A. 33.3 13.3 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 0 0 14 14 7 20 7 7 14 14 14 14 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 27 7 7 0 0 20 7 14 0 7 7 0 20 % D
% Glu: 0 14 54 0 14 7 0 7 0 0 0 0 14 0 7 % E
% Phe: 0 7 0 0 0 0 0 0 7 0 0 0 7 14 0 % F
% Gly: 0 7 0 0 0 0 7 0 0 40 0 0 0 0 20 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 0 14 20 14 14 0 7 0 7 0 0 0 0 % I
% Lys: 20 14 0 0 7 14 7 20 7 0 47 47 0 40 14 % K
% Leu: 0 54 0 0 0 0 0 7 54 0 0 0 14 7 0 % L
% Met: 0 0 7 0 0 0 7 0 7 0 0 0 0 0 0 % M
% Asn: 20 0 0 0 0 0 20 7 0 7 0 7 0 14 20 % N
% Pro: 0 0 0 47 0 0 0 0 7 7 7 0 0 0 14 % P
% Gln: 27 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % Q
% Arg: 7 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % R
% Ser: 14 0 0 7 0 0 7 27 0 0 20 7 0 0 7 % S
% Thr: 0 0 0 0 7 7 14 0 0 14 0 14 7 0 0 % T
% Val: 0 0 14 14 34 0 7 0 0 7 0 7 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 54 0 7 0 0 0 0 40 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _