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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDIA4
All Species:
27.27
Human Site:
T431
Identified Species:
42.86
UniProt:
P13667
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13667
NP_004902.1
645
72932
T431
S
F
D
Y
R
A
A
T
Q
F
W
R
S
K
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_539831
628
70318
T414
P
P
R
P
A
S
A
T
Q
F
W
R
N
K
V
Cat
Felis silvestris
Mouse
Mus musculus
P08003
638
71955
T424
S
F
D
Y
R
A
A
T
Q
F
W
R
N
K
V
Rat
Rattus norvegicus
P38659
643
72702
T429
S
F
D
Y
R
T
A
T
Q
F
W
R
N
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q8JG64
505
56163
A300
H
K
L
S
F
A
V
A
S
R
K
T
F
G
H
Frog
Xenopus laevis
NP_001088331
637
71736
T424
S
F
D
Y
R
T
A
T
Q
Y
W
R
S
K
V
Zebra Danio
Brachydanio rerio
NP_956073
645
72696
T431
S
F
D
Y
R
V
A
T
Q
F
W
R
S
K
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
I291
D
D
I
L
F
V
T
I
S
S
D
E
E
D
H
Honey Bee
Apis mellifera
XP_623282
490
55838
L285
V
A
K
D
F
P
N
L
N
F
A
I
S
S
K
Nematode Worm
Caenorhab. elegans
P34329
618
69779
S400
S
V
Q
Y
R
E
G
S
E
Y
W
R
S
K
V
Sea Urchin
Strong. purpuratus
XP_791396
637
72173
T419
S
F
D
H
R
V
A
T
E
I
Y
R
Q
K
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P52588
513
57078
L307
K
D
K
E
I
K
F
L
I
G
D
I
E
A
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SRG3
508
56346
G303
Q
S
L
A
F
L
V
G
D
A
E
S
S
Q
G
Baker's Yeast
Sacchar. cerevisiae
P17967
522
58209
H317
Q
F
P
L
F
A
I
H
D
M
T
E
D
L
K
Red Bread Mold
Neurospora crassa
Q92249
369
39263
A164
G
D
K
N
V
L
V
A
F
T
A
P
W
C
G
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
81.7
N.A.
87.7
88
N.A.
N.A.
32.8
72
72.2
N.A.
30.2
30.8
47.4
53.1
Protein Similarity:
100
N.A.
N.A.
89.1
N.A.
93.6
94.2
N.A.
N.A.
47.4
84.6
84.8
N.A.
47.5
47.4
63
68.9
P-Site Identity:
100
N.A.
N.A.
53.3
N.A.
93.3
86.6
N.A.
N.A.
6.6
86.6
93.3
N.A.
0
13.3
53.3
53.3
P-Site Similarity:
100
N.A.
N.A.
66.6
N.A.
100
93.3
N.A.
N.A.
6.6
93.3
93.3
N.A.
0
13.3
73.3
80
Percent
Protein Identity:
N.A.
29.6
N.A.
30.3
23.5
22.3
Protein Similarity:
N.A.
44.5
N.A.
48.5
37.5
34.8
P-Site Identity:
N.A.
0
N.A.
6.6
13.3
0
P-Site Similarity:
N.A.
0
N.A.
13.3
13.3
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
7
7
27
47
14
0
7
14
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% C
% Asp:
7
20
40
7
0
0
0
0
14
0
14
0
7
7
0
% D
% Glu:
0
0
0
7
0
7
0
0
14
0
7
14
14
0
0
% E
% Phe:
0
47
0
0
34
0
7
0
7
40
0
0
7
0
0
% F
% Gly:
7
0
0
0
0
0
7
7
0
7
0
0
0
7
14
% G
% His:
7
0
0
7
0
0
0
7
0
0
0
0
0
0
14
% H
% Ile:
0
0
7
0
7
0
7
7
7
7
0
14
0
0
7
% I
% Lys:
7
7
20
0
0
7
0
0
0
0
7
0
0
54
14
% K
% Leu:
0
0
14
14
0
14
0
14
0
0
0
0
0
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
0
0
7
0
0
7
0
7
0
0
0
20
0
0
% N
% Pro:
7
7
7
7
0
7
0
0
0
0
0
7
0
0
0
% P
% Gln:
14
0
7
0
0
0
0
0
40
0
0
0
7
7
0
% Q
% Arg:
0
0
7
0
47
0
0
0
0
7
0
54
0
0
0
% R
% Ser:
47
7
0
7
0
7
0
7
14
7
0
7
40
7
7
% S
% Thr:
0
0
0
0
0
14
7
47
0
7
7
7
0
0
0
% T
% Val:
7
7
0
0
7
20
20
0
0
0
0
0
0
0
47
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
47
0
7
0
0
% W
% Tyr:
0
0
0
40
0
0
0
0
0
14
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _