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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDIA4 All Species: 19.7
Human Site: Y151 Identified Species: 30.95
UniProt: P13667 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P13667 NP_004902.1 645 72932 Y151 K K G Q A V D Y E G S R T Q E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_539831 628 70318 A145 K I L K K G E A V D Y E G S R
Cat Felis silvestris
Mouse Mus musculus P08003 638 71955 Y144 K K G Q A V D Y D G S R T Q E
Rat Rattus norvegicus P38659 643 72702 Y149 K K G Q A V D Y D G S R T Q E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q8JG64 505 56163 A33 D V V E L S D A D F E S G L A
Frog Xenopus laevis NP_001088331 637 71736 Y144 K K G Q P I D Y D G A R T Q E
Zebra Danio Brachydanio rerio NP_956073 645 72696 Y151 K K G E P L D Y D G D R S E H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54399 496 55763 K24 A S A E A E V K V E E G V L V
Honey Bee Apis mellifera XP_623282 490 55838 A18 L V F A S V L A E E K D V V E
Nematode Worm Caenorhab. elegans P34329 618 69779 D120 K D G K G P N D Y D G G R D E
Sea Urchin Strong. purpuratus XP_791396 637 72173 Y140 R K G K P F A Y D G P R E K N
Poplar Tree Populus trichocarpa
Maize Zea mays P52588 513 57078 D40 G E A V L T L D V D S F D E A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SRG3 508 56346 H36 E F V L T L D H S N F T E T I
Baker's Yeast Sacchar. cerevisiae P17967 522 58209 D50 N E Y I Q S H D L V L A E F F
Red Bread Mold Neurospora crassa Q92249 369 39263
Conservation
Percent
Protein Identity: 100 N.A. N.A. 81.7 N.A. 87.7 88 N.A. N.A. 32.8 72 72.2 N.A. 30.2 30.8 47.4 53.1
Protein Similarity: 100 N.A. N.A. 89.1 N.A. 93.6 94.2 N.A. N.A. 47.4 84.6 84.8 N.A. 47.5 47.4 63 68.9
P-Site Identity: 100 N.A. N.A. 6.6 N.A. 93.3 93.3 N.A. N.A. 6.6 73.3 46.6 N.A. 6.6 20 20 33.3
P-Site Similarity: 100 N.A. N.A. 20 N.A. 100 100 N.A. N.A. 20 93.3 80 N.A. 13.3 26.6 33.3 60
Percent
Protein Identity: N.A. 29.6 N.A. 30.3 23.5 22.3
Protein Similarity: N.A. 44.5 N.A. 48.5 37.5 34.8
P-Site Identity: N.A. 6.6 N.A. 6.6 0 0
P-Site Similarity: N.A. 20 N.A. 26.6 6.6 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 14 7 27 0 7 20 0 0 7 7 0 0 14 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 7 0 0 0 0 47 20 40 20 7 7 7 7 0 % D
% Glu: 7 14 0 20 0 7 7 0 14 14 14 7 20 14 40 % E
% Phe: 0 7 7 0 0 7 0 0 0 7 7 7 0 7 7 % F
% Gly: 7 0 47 0 7 7 0 0 0 40 7 14 14 0 0 % G
% His: 0 0 0 0 0 0 7 7 0 0 0 0 0 0 7 % H
% Ile: 0 7 0 7 0 7 0 0 0 0 0 0 0 0 7 % I
% Lys: 47 40 0 20 7 0 0 7 0 0 7 0 0 7 0 % K
% Leu: 7 0 7 7 14 14 14 0 7 0 7 0 0 14 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 0 0 0 0 0 7 0 0 7 0 0 0 0 7 % N
% Pro: 0 0 0 0 20 7 0 0 0 0 7 0 0 0 0 % P
% Gln: 0 0 0 27 7 0 0 0 0 0 0 0 0 27 0 % Q
% Arg: 7 0 0 0 0 0 0 0 0 0 0 40 7 0 7 % R
% Ser: 0 7 0 0 7 14 0 0 7 0 27 7 7 7 0 % S
% Thr: 0 0 0 0 7 7 0 0 0 0 0 7 27 7 0 % T
% Val: 0 14 14 7 0 27 7 0 20 7 0 0 14 7 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 0 0 0 0 40 7 0 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _