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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDIA4
All Species:
21.82
Human Site:
Y252
Identified Species:
34.29
UniProt:
P13667
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13667
NP_004902.1
645
72932
Y252
K
R
F
D
V
S
G
Y
P
T
L
K
I
F
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_539831
628
70318
R243
A
E
T
D
L
A
K
R
F
E
V
S
S
Y
P
Cat
Felis silvestris
Mouse
Mus musculus
P08003
638
71955
Y245
K
R
F
D
V
S
G
Y
P
T
L
K
I
F
R
Rat
Rattus norvegicus
P38659
643
72702
Y250
K
R
F
D
V
S
G
Y
P
T
L
K
I
F
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q8JG64
505
56163
A130
V
S
H
L
K
K
Q
A
G
P
A
S
V
A
L
Frog
Xenopus laevis
NP_001088331
637
71736
F245
S
K
Y
G
V
T
G
F
P
T
L
K
I
F
R
Zebra Danio
Brachydanio rerio
NP_956073
645
72696
Y252
T
R
F
G
V
S
G
Y
P
T
L
K
I
F
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
Q121
V
E
Y
S
G
G
R
Q
A
A
D
I
I
A
W
Honey Bee
Apis mellifera
XP_623282
490
55838
P115
F
V
S
D
Y
N
G
P
R
E
A
V
G
I
A
Nematode Worm
Caenorhab. elegans
P34329
618
69779
Y222
T
K
Y
G
V
S
G
Y
P
T
M
K
I
I
R
Sea Urchin
Strong. purpuratus
XP_791396
637
72173
Y241
T
R
Y
D
V
S
G
Y
P
T
L
K
I
F
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P52588
513
57078
V137
P
R
E
A
D
G
I
V
D
Y
L
K
K
Q
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SRG3
508
56346
T133
R
E
A
E
G
I
V
T
Y
L
K
K
Q
S
G
Baker's Yeast
Sacchar. cerevisiae
P17967
522
58209
A147
Q
P
A
V
A
V
V
A
D
L
P
A
Y
L
A
Red Bread Mold
Neurospora crassa
Q92249
369
39263
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
81.7
N.A.
87.7
88
N.A.
N.A.
32.8
72
72.2
N.A.
30.2
30.8
47.4
53.1
Protein Similarity:
100
N.A.
N.A.
89.1
N.A.
93.6
94.2
N.A.
N.A.
47.4
84.6
84.8
N.A.
47.5
47.4
63
68.9
P-Site Identity:
100
N.A.
N.A.
6.6
N.A.
100
100
N.A.
N.A.
0
60
86.6
N.A.
6.6
13.3
60
86.6
P-Site Similarity:
100
N.A.
N.A.
33.3
N.A.
100
100
N.A.
N.A.
6.6
86.6
86.6
N.A.
13.3
20
80
93.3
Percent
Protein Identity:
N.A.
29.6
N.A.
30.3
23.5
22.3
Protein Similarity:
N.A.
44.5
N.A.
48.5
37.5
34.8
P-Site Identity:
N.A.
20
N.A.
6.6
0
0
P-Site Similarity:
N.A.
20
N.A.
20
6.6
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
14
7
7
7
0
14
7
7
14
7
0
14
14
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
40
7
0
0
0
14
0
7
0
0
0
0
% D
% Glu:
0
20
7
7
0
0
0
0
0
14
0
0
0
0
0
% E
% Phe:
7
0
27
0
0
0
0
7
7
0
0
0
0
40
0
% F
% Gly:
0
0
0
20
14
14
54
0
7
0
0
0
7
0
7
% G
% His:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
7
7
0
0
0
0
7
54
14
0
% I
% Lys:
20
14
0
0
7
7
7
0
0
0
7
60
7
0
0
% K
% Leu:
0
0
0
7
7
0
0
0
0
14
47
0
0
7
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% M
% Asn:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% N
% Pro:
7
7
0
0
0
0
0
7
47
7
7
0
0
0
7
% P
% Gln:
7
0
0
0
0
0
7
7
0
0
0
0
7
7
0
% Q
% Arg:
7
40
0
0
0
0
7
7
7
0
0
0
0
0
47
% R
% Ser:
7
7
7
7
0
40
0
0
0
0
0
14
7
7
0
% S
% Thr:
20
0
7
0
0
7
0
7
0
47
0
0
0
0
0
% T
% Val:
14
7
0
7
47
7
14
7
0
0
7
7
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% W
% Tyr:
0
0
27
0
7
0
0
40
7
7
0
0
7
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _