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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDIA4
All Species:
18.79
Human Site:
Y334
Identified Species:
29.52
UniProt:
P13667
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13667
NP_004902.1
645
72932
Y334
A
N
N
L
R
E
D
Y
K
F
H
H
T
F
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_539831
628
70318
Y317
K
A
E
S
D
P
A
Y
Q
Q
Y
Q
D
A
A
Cat
Felis silvestris
Mouse
Mus musculus
P08003
638
71955
Y327
A
N
N
L
R
E
D
Y
K
F
H
H
T
F
S
Rat
Rattus norvegicus
P38659
643
72702
Y332
A
N
T
L
R
E
D
Y
K
F
H
H
T
F
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q8JG64
505
56163
L203
E
D
G
E
G
V
V
L
Y
R
P
S
R
L
A
Frog
Xenopus laevis
NP_001088331
637
71736
Y327
A
N
S
L
R
E
D
Y
K
F
Y
H
T
F
S
Zebra Danio
Brachydanio rerio
NP_956073
645
72696
Y334
C
N
S
L
R
E
D
Y
K
F
M
H
T
F
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
A194
S
S
N
A
D
V
I
A
K
Y
E
A
K
D
N
Honey Bee
Apis mellifera
XP_623282
490
55838
S188
F
A
H
T
T
A
K
S
L
M
E
K
E
G
Y
Nematode Worm
Caenorhab. elegans
P34329
618
69779
F303
A
E
M
L
R
E
E
F
K
T
M
G
H
T
S
Sea Urchin
Strong. purpuratus
XP_791396
637
72173
N322
A
G
N
G
L
R
D
N
Y
R
F
A
H
V
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P52588
513
57078
A210
N
H
L
P
R
G
D
A
A
V
E
R
P
L
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SRG3
508
56346
V206
F
L
P
R
G
E
S
V
E
G
P
A
V
R
L
Baker's Yeast
Sacchar. cerevisiae
P17967
522
58209
K220
P
V
V
Y
N
G
K
K
A
D
I
A
D
A
D
Red Bread Mold
Neurospora crassa
Q92249
369
39263
L67
Y
E
E
L
A
T
A
L
E
Y
A
K
D
K
V
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
81.7
N.A.
87.7
88
N.A.
N.A.
32.8
72
72.2
N.A.
30.2
30.8
47.4
53.1
Protein Similarity:
100
N.A.
N.A.
89.1
N.A.
93.6
94.2
N.A.
N.A.
47.4
84.6
84.8
N.A.
47.5
47.4
63
68.9
P-Site Identity:
100
N.A.
N.A.
6.6
N.A.
100
93.3
N.A.
N.A.
0
86.6
73.3
N.A.
13.3
0
40
20
P-Site Similarity:
100
N.A.
N.A.
26.6
N.A.
100
93.3
N.A.
N.A.
13.3
100
86.6
N.A.
40
6.6
53.3
20
Percent
Protein Identity:
N.A.
29.6
N.A.
30.3
23.5
22.3
Protein Similarity:
N.A.
44.5
N.A.
48.5
37.5
34.8
P-Site Identity:
N.A.
13.3
N.A.
6.6
0
6.6
P-Site Similarity:
N.A.
20
N.A.
13.3
0
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
40
14
0
7
7
7
14
14
14
0
7
27
0
14
14
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
14
0
47
0
0
7
0
0
20
7
7
% D
% Glu:
7
14
14
7
0
47
7
0
14
0
20
0
7
0
0
% E
% Phe:
14
0
0
0
0
0
0
7
0
34
7
0
0
34
7
% F
% Gly:
0
7
7
7
14
14
0
0
0
7
0
7
0
7
0
% G
% His:
0
7
7
0
0
0
0
0
0
0
20
34
14
0
0
% H
% Ile:
0
0
0
0
0
0
7
0
0
0
7
0
0
0
0
% I
% Lys:
7
0
0
0
0
0
14
7
47
0
0
14
7
7
0
% K
% Leu:
0
7
7
47
7
0
0
14
7
0
0
0
0
14
7
% L
% Met:
0
0
7
0
0
0
0
0
0
7
14
0
0
0
0
% M
% Asn:
7
34
27
0
7
0
0
7
0
0
0
0
0
0
14
% N
% Pro:
7
0
7
7
0
7
0
0
0
0
14
0
7
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
7
7
0
7
0
0
0
% Q
% Arg:
0
0
0
7
47
7
0
0
0
14
0
7
7
7
0
% R
% Ser:
7
7
14
7
0
0
7
7
0
0
0
7
0
0
34
% S
% Thr:
0
0
7
7
7
7
0
0
0
7
0
0
34
7
0
% T
% Val:
0
7
7
0
0
14
7
7
0
7
0
0
7
7
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
7
0
0
0
40
14
14
14
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _