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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDIA4 All Species: 18.79
Human Site: Y334 Identified Species: 29.52
UniProt: P13667 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P13667 NP_004902.1 645 72932 Y334 A N N L R E D Y K F H H T F S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_539831 628 70318 Y317 K A E S D P A Y Q Q Y Q D A A
Cat Felis silvestris
Mouse Mus musculus P08003 638 71955 Y327 A N N L R E D Y K F H H T F S
Rat Rattus norvegicus P38659 643 72702 Y332 A N T L R E D Y K F H H T F S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q8JG64 505 56163 L203 E D G E G V V L Y R P S R L A
Frog Xenopus laevis NP_001088331 637 71736 Y327 A N S L R E D Y K F Y H T F S
Zebra Danio Brachydanio rerio NP_956073 645 72696 Y334 C N S L R E D Y K F M H T F N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54399 496 55763 A194 S S N A D V I A K Y E A K D N
Honey Bee Apis mellifera XP_623282 490 55838 S188 F A H T T A K S L M E K E G Y
Nematode Worm Caenorhab. elegans P34329 618 69779 F303 A E M L R E E F K T M G H T S
Sea Urchin Strong. purpuratus XP_791396 637 72173 N322 A G N G L R D N Y R F A H V F
Poplar Tree Populus trichocarpa
Maize Zea mays P52588 513 57078 A210 N H L P R G D A A V E R P L V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SRG3 508 56346 V206 F L P R G E S V E G P A V R L
Baker's Yeast Sacchar. cerevisiae P17967 522 58209 K220 P V V Y N G K K A D I A D A D
Red Bread Mold Neurospora crassa Q92249 369 39263 L67 Y E E L A T A L E Y A K D K V
Conservation
Percent
Protein Identity: 100 N.A. N.A. 81.7 N.A. 87.7 88 N.A. N.A. 32.8 72 72.2 N.A. 30.2 30.8 47.4 53.1
Protein Similarity: 100 N.A. N.A. 89.1 N.A. 93.6 94.2 N.A. N.A. 47.4 84.6 84.8 N.A. 47.5 47.4 63 68.9
P-Site Identity: 100 N.A. N.A. 6.6 N.A. 100 93.3 N.A. N.A. 0 86.6 73.3 N.A. 13.3 0 40 20
P-Site Similarity: 100 N.A. N.A. 26.6 N.A. 100 93.3 N.A. N.A. 13.3 100 86.6 N.A. 40 6.6 53.3 20
Percent
Protein Identity: N.A. 29.6 N.A. 30.3 23.5 22.3
Protein Similarity: N.A. 44.5 N.A. 48.5 37.5 34.8
P-Site Identity: N.A. 13.3 N.A. 6.6 0 6.6
P-Site Similarity: N.A. 20 N.A. 13.3 0 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 40 14 0 7 7 7 14 14 14 0 7 27 0 14 14 % A
% Cys: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 0 14 0 47 0 0 7 0 0 20 7 7 % D
% Glu: 7 14 14 7 0 47 7 0 14 0 20 0 7 0 0 % E
% Phe: 14 0 0 0 0 0 0 7 0 34 7 0 0 34 7 % F
% Gly: 0 7 7 7 14 14 0 0 0 7 0 7 0 7 0 % G
% His: 0 7 7 0 0 0 0 0 0 0 20 34 14 0 0 % H
% Ile: 0 0 0 0 0 0 7 0 0 0 7 0 0 0 0 % I
% Lys: 7 0 0 0 0 0 14 7 47 0 0 14 7 7 0 % K
% Leu: 0 7 7 47 7 0 0 14 7 0 0 0 0 14 7 % L
% Met: 0 0 7 0 0 0 0 0 0 7 14 0 0 0 0 % M
% Asn: 7 34 27 0 7 0 0 7 0 0 0 0 0 0 14 % N
% Pro: 7 0 7 7 0 7 0 0 0 0 14 0 7 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 7 7 0 7 0 0 0 % Q
% Arg: 0 0 0 7 47 7 0 0 0 14 0 7 7 7 0 % R
% Ser: 7 7 14 7 0 0 7 7 0 0 0 7 0 0 34 % S
% Thr: 0 0 7 7 7 7 0 0 0 7 0 0 34 7 0 % T
% Val: 0 7 7 0 0 14 7 7 0 7 0 0 7 7 14 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 7 0 0 0 40 14 14 14 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _