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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDIA4
All Species:
14.24
Human Site:
Y367
Identified Species:
22.38
UniProt:
P13667
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13667
NP_004902.1
645
72932
Y367
P
E
K
F
Q
S
K
Y
E
P
R
S
H
M
M
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_539831
628
70318
G350
K
F
L
K
V
S
S
G
K
L
V
V
M
Q
P
Cat
Felis silvestris
Mouse
Mus musculus
P08003
638
71955
Y360
P
E
K
F
Q
S
K
Y
E
P
R
F
H
V
M
Rat
Rattus norvegicus
P38659
643
72702
Y365
P
E
K
F
Q
S
K
Y
E
P
R
M
H
V
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q8JG64
505
56163
E236
K
I
K
K
F
I
Q
E
N
I
F
G
I
C
P
Frog
Xenopus laevis
NP_001088331
637
71736
Y360
P
E
K
F
Q
S
K
Y
E
A
K
K
Y
I
L
Zebra Danio
Brachydanio rerio
NP_956073
645
72696
H367
P
E
K
F
R
S
K
H
E
S
A
S
H
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
K227
L
N
E
E
N
L
K
K
F
A
Q
V
Q
S
L
Honey Bee
Apis mellifera
XP_623282
490
55838
T221
N
I
V
K
Y
D
E
T
M
G
D
I
Q
E
F
Nematode Worm
Caenorhab. elegans
P34329
618
69779
K336
Y
P
S
L
F
H
S
K
F
E
P
K
S
R
T
Sea Urchin
Strong. purpuratus
XP_791396
637
72173
K355
L
P
E
R
F
R
S
K
Y
E
P
W
R
H
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P52588
513
57078
D243
A
A
L
M
K
F
I
D
A
S
T
I
P
R
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SRG3
508
56346
S239
L
E
K
F
V
K
E
S
S
I
P
L
V
T
V
Baker's Yeast
Sacchar. cerevisiae
P17967
522
58209
V253
G
S
V
F
A
Q
Y
V
E
S
G
L
P
L
G
Red Bread Mold
Neurospora crassa
Q92249
369
39263
K100
V
Q
G
F
P
T
L
K
F
F
D
G
K
S
E
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
81.7
N.A.
87.7
88
N.A.
N.A.
32.8
72
72.2
N.A.
30.2
30.8
47.4
53.1
Protein Similarity:
100
N.A.
N.A.
89.1
N.A.
93.6
94.2
N.A.
N.A.
47.4
84.6
84.8
N.A.
47.5
47.4
63
68.9
P-Site Identity:
100
N.A.
N.A.
6.6
N.A.
86.6
86.6
N.A.
N.A.
6.6
60
60
N.A.
6.6
0
0
0
P-Site Similarity:
100
N.A.
N.A.
13.3
N.A.
93.3
93.3
N.A.
N.A.
13.3
86.6
80
N.A.
26.6
6.6
0
13.3
Percent
Protein Identity:
N.A.
29.6
N.A.
30.3
23.5
22.3
Protein Similarity:
N.A.
44.5
N.A.
48.5
37.5
34.8
P-Site Identity:
N.A.
0
N.A.
20
13.3
6.6
P-Site Similarity:
N.A.
13.3
N.A.
33.3
20
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
7
0
0
0
7
14
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% C
% Asp:
0
0
0
0
0
7
0
7
0
0
14
0
0
0
0
% D
% Glu:
0
40
14
7
0
0
14
7
40
14
0
0
0
7
7
% E
% Phe:
0
7
0
54
20
7
0
0
20
7
7
7
0
0
7
% F
% Gly:
7
0
7
0
0
0
0
7
0
7
7
14
0
0
7
% G
% His:
0
0
0
0
0
7
0
7
0
0
0
0
27
7
0
% H
% Ile:
0
14
0
0
0
7
7
0
0
14
0
14
7
7
0
% I
% Lys:
14
0
47
20
7
7
40
27
7
0
7
14
7
0
0
% K
% Leu:
20
0
14
7
0
7
7
0
0
7
0
14
0
7
20
% L
% Met:
0
0
0
7
0
0
0
0
7
0
0
7
7
7
20
% M
% Asn:
7
7
0
0
7
0
0
0
7
0
0
0
0
0
0
% N
% Pro:
34
14
0
0
7
0
0
0
0
20
20
0
14
0
14
% P
% Gln:
0
7
0
0
27
7
7
0
0
0
7
0
14
7
0
% Q
% Arg:
0
0
0
7
7
7
0
0
0
0
20
0
7
14
0
% R
% Ser:
0
7
7
0
0
40
20
7
7
20
0
14
7
20
0
% S
% Thr:
0
0
0
0
0
7
0
7
0
0
7
0
0
7
7
% T
% Val:
7
0
14
0
14
0
0
7
0
0
7
14
7
14
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% W
% Tyr:
7
0
0
0
7
0
7
27
7
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _