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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDIA4
All Species:
16.36
Human Site:
Y458
Identified Species:
25.71
UniProt:
P13667
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13667
NP_004902.1
645
72932
Y458
A
I
A
D
E
E
D
Y
A
G
E
V
K
D
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_539831
628
70318
F441
A
V
A
D
E
D
D
F
A
S
E
V
R
D
L
Cat
Felis silvestris
Mouse
Mus musculus
P08003
638
71955
Y451
A
I
A
D
E
E
D
Y
A
T
E
V
K
D
L
Rat
Rattus norvegicus
P38659
643
72702
Y456
A
I
A
D
E
E
D
Y
A
T
E
V
K
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q8JG64
505
56163
R327
E
A
P
V
V
A
I
R
T
A
K
G
D
K
F
Frog
Xenopus laevis
NP_001088331
637
71736
Y451
A
I
A
N
E
D
D
Y
T
S
E
L
K
D
L
Zebra Danio
Brachydanio rerio
NP_956073
645
72696
Y458
A
I
A
D
E
E
D
Y
A
D
E
L
K
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
I318
E
V
P
T
I
R
L
I
K
L
E
E
D
M
A
Honey Bee
Apis mellifera
XP_623282
490
55838
P312
D
F
V
K
G
D
K
P
V
I
L
A
R
N
I
Nematode Worm
Caenorhab. elegans
P34329
618
69779
E427
K
F
A
V
A
D
E
E
E
F
A
K
E
L
E
Sea Urchin
Strong. purpuratus
XP_791396
637
72173
E446
H
F
A
I
A
D
E
E
E
F
A
A
E
M
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P52588
513
57078
Q334
Q
T
P
L
I
L
I
Q
D
G
D
S
K
K
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SRG3
508
56346
P330
P
L
I
I
I
Q
T
P
D
N
K
K
Y
L
K
Baker's Yeast
Sacchar. cerevisiae
P17967
522
58209
L344
E
L
S
D
K
I
V
L
E
S
K
A
I
E
S
Red Bread Mold
Neurospora crassa
Q92249
369
39263
P191
A
A
T
F
A
S
D
P
E
I
T
I
A
K
V
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
81.7
N.A.
87.7
88
N.A.
N.A.
32.8
72
72.2
N.A.
30.2
30.8
47.4
53.1
Protein Similarity:
100
N.A.
N.A.
89.1
N.A.
93.6
94.2
N.A.
N.A.
47.4
84.6
84.8
N.A.
47.5
47.4
63
68.9
P-Site Identity:
100
N.A.
N.A.
66.6
N.A.
93.3
93.3
N.A.
N.A.
0
66.6
80
N.A.
6.6
0
6.6
6.6
P-Site Similarity:
100
N.A.
N.A.
93.3
N.A.
93.3
93.3
N.A.
N.A.
6.6
86.6
86.6
N.A.
13.3
26.6
26.6
26.6
Percent
Protein Identity:
N.A.
29.6
N.A.
30.3
23.5
22.3
Protein Similarity:
N.A.
44.5
N.A.
48.5
37.5
34.8
P-Site Identity:
N.A.
13.3
N.A.
0
6.6
13.3
P-Site Similarity:
N.A.
20
N.A.
20
40
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
47
14
54
0
20
7
0
0
34
7
14
20
7
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
40
0
34
47
0
14
7
7
0
14
34
0
% D
% Glu:
20
0
0
0
40
27
14
14
27
0
47
7
14
7
7
% E
% Phe:
0
20
0
7
0
0
0
7
0
14
0
0
0
0
14
% F
% Gly:
0
0
0
0
7
0
0
0
0
14
0
7
0
0
0
% G
% His:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
34
7
14
20
7
14
7
0
14
0
7
7
0
7
% I
% Lys:
7
0
0
7
7
0
7
0
7
0
20
14
40
20
14
% K
% Leu:
0
14
0
7
0
7
7
7
0
7
7
14
0
14
40
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
14
0
% M
% Asn:
0
0
0
7
0
0
0
0
0
7
0
0
0
7
0
% N
% Pro:
7
0
20
0
0
0
0
20
0
0
0
0
0
0
0
% P
% Gln:
7
0
0
0
0
7
0
7
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
7
0
7
0
0
0
0
14
0
0
% R
% Ser:
0
0
7
0
0
7
0
0
0
20
0
7
0
7
7
% S
% Thr:
0
7
7
7
0
0
7
0
14
14
7
0
0
0
0
% T
% Val:
0
14
7
14
7
0
7
0
7
0
0
27
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
34
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _