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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDIA4 All Species: 30
Human Site: Y604 Identified Species: 47.14
UniProt: P13667 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.21
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P13667 NP_004902.1 645 72932 Y604 V E G F P T I Y F A P S G D K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_539831 628 70318 Y587 V D G F P T I Y F A P R G D K
Cat Felis silvestris
Mouse Mus musculus P08003 638 71955 Y597 V E G F P T I Y F A P S G D K
Rat Rattus norvegicus P38659 643 72702 Y602 V E G F P T I Y F A P S G D K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q8JG64 505 56163 E470 K K Y E G G R E V S D F I S Y
Frog Xenopus laevis NP_001088331 637 71736 Y597 V E G F P T I Y F A P Q N N K
Zebra Danio Brachydanio rerio NP_956073 645 72696 Y604 V E G F P T I Y F A P S N N K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54399 496 55763 T461 I D F N L D R T L D D F V K F
Honey Bee Apis mellifera XP_623282 490 55838 G455 N P V K Y E G G R E L D D F I
Nematode Worm Caenorhab. elegans P34329 618 69779 Y578 V E G F P T I Y F A P A G K K
Sea Urchin Strong. purpuratus XP_791396 637 72173 Y595 T T G F P T I Y F S K A G D K
Poplar Tree Populus trichocarpa
Maize Zea mays P52588 513 57078 D478 R T A D D I V D F I K K S K E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SRG3 508 56346 N473 R T K E D F I N F V E K N S E
Baker's Yeast Sacchar. cerevisiae P17967 522 58209 D487 I K E N G H F D V D G K A L Y
Red Bread Mold Neurospora crassa Q92249 369 39263 L334 F A R L E G I L K K G G L A P
Conservation
Percent
Protein Identity: 100 N.A. N.A. 81.7 N.A. 87.7 88 N.A. N.A. 32.8 72 72.2 N.A. 30.2 30.8 47.4 53.1
Protein Similarity: 100 N.A. N.A. 89.1 N.A. 93.6 94.2 N.A. N.A. 47.4 84.6 84.8 N.A. 47.5 47.4 63 68.9
P-Site Identity: 100 N.A. N.A. 86.6 N.A. 100 100 N.A. N.A. 0 80 86.6 N.A. 0 0 86.6 66.6
P-Site Similarity: 100 N.A. N.A. 93.3 N.A. 100 100 N.A. N.A. 13.3 86.6 93.3 N.A. 13.3 0 93.3 80
Percent
Protein Identity: N.A. 29.6 N.A. 30.3 23.5 22.3
Protein Similarity: N.A. 44.5 N.A. 48.5 37.5 34.8
P-Site Identity: N.A. 6.6 N.A. 13.3 0 6.6
P-Site Similarity: N.A. 20 N.A. 20 13.3 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 7 0 0 0 0 0 0 47 0 14 7 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 14 0 7 14 7 0 14 0 14 14 7 7 34 0 % D
% Glu: 0 40 7 14 7 7 0 7 0 7 7 0 0 0 14 % E
% Phe: 7 0 7 54 0 7 7 0 67 0 0 14 0 7 7 % F
% Gly: 0 0 54 0 14 14 7 7 0 0 14 7 40 0 0 % G
% His: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % H
% Ile: 14 0 0 0 0 7 67 0 0 7 0 0 7 0 7 % I
% Lys: 7 14 7 7 0 0 0 0 7 7 14 20 0 20 54 % K
% Leu: 0 0 0 7 7 0 0 7 7 0 7 0 7 7 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 0 0 14 0 0 0 7 0 0 0 0 20 14 0 % N
% Pro: 0 7 0 0 54 0 0 0 0 0 47 0 0 0 7 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % Q
% Arg: 14 0 7 0 0 0 14 0 7 0 0 7 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 14 0 27 7 14 0 % S
% Thr: 7 20 0 0 0 54 0 7 0 0 0 0 0 0 0 % T
% Val: 47 0 7 0 0 0 7 0 14 7 0 0 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 0 7 0 0 54 0 0 0 0 0 0 14 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _