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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TPT1 All Species: 26.06
Human Site: S82 Identified Species: 47.78
UniProt: P13693 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P13693 NP_003286.1 172 19595 S82 N H H L Q E T S F T K E A Y K
Chimpanzee Pan troglodytes XP_001146432 172 19563 S82 N H H L Q E T S F T K E G Y K
Rhesus Macaque Macaca mulatta XP_001112392 172 19576 S82 N H H L Q E T S F T K E A Y K
Dog Lupus familis XP_856352 152 17083 M74 I T G V D I V M N H H L Q E T
Cat Felis silvestris
Mouse Mus musculus NP_033455 172 19444 S82 N H H L Q E T S F T K E A Y K
Rat Rattus norvegicus P63029 172 19444 S82 N H H L Q E T S F T K E A Y K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P43347 172 19512 S82 N H H L Q E T S F T K E S Y K
Frog Xenopus laevis Q7ZYF2 172 19508 G82 N H K L Q E T G F T K D S Y K
Zebra Danio Brachydanio rerio Q9DGK4 171 19006 S81 N H K L Q E T S Y D K K S Y T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VGS2 172 19619 F80 R L T E C F A F G D K K S Y T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays Q8H6A5 167 18672 P80 F R L Q E Q P P F D K K S F V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P35691 167 18723 F78 F R L Q Q T A F D K K S F L T
Red Bread Mold Neurospora crassa Q7RYV5 170 19009 K81 Q S T Q F D K K G Y L V Y L K
Conservation
Percent
Protein Identity: 100 99.4 99.4 88.3 N.A. 95.9 95.9 N.A. N.A. 90.1 68.5 67.4 N.A. 50.5 N.A. N.A. N.A.
Protein Similarity: 100 99.4 100 88.3 N.A. 98.8 98.8 N.A. N.A. 97 80.2 83.7 N.A. 70.9 N.A. N.A. N.A.
P-Site Identity: 100 93.3 100 0 N.A. 100 100 N.A. N.A. 93.3 73.3 60 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 93.3 100 6.6 N.A. 100 100 N.A. N.A. 100 86.6 80 N.A. 26.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. 39.5 N.A. N.A. 41.8 45.9
Protein Similarity: N.A. 57.5 N.A. N.A. 63.9 66.2
P-Site Identity: N.A. 13.3 N.A. N.A. 13.3 6.6
P-Site Similarity: N.A. 46.6 N.A. N.A. 13.3 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 16 0 0 0 0 0 31 0 0 % A
% Cys: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 8 0 0 8 24 0 8 0 0 0 % D
% Glu: 0 0 0 8 8 62 0 0 0 0 0 47 0 8 0 % E
% Phe: 16 0 0 0 8 8 0 16 62 0 0 0 8 8 0 % F
% Gly: 0 0 8 0 0 0 0 8 16 0 0 0 8 0 0 % G
% His: 0 62 47 0 0 0 0 0 0 8 8 0 0 0 0 % H
% Ile: 8 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 16 0 0 0 8 8 0 8 85 24 0 0 62 % K
% Leu: 0 8 16 62 0 0 0 0 0 0 8 8 0 16 0 % L
% Met: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % M
% Asn: 62 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 8 8 0 0 0 0 0 0 0 % P
% Gln: 8 0 0 24 70 8 0 0 0 0 0 0 8 0 0 % Q
% Arg: 8 16 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 8 0 0 0 0 0 54 0 0 0 8 39 0 0 % S
% Thr: 0 8 16 0 0 8 62 0 0 54 0 0 0 0 31 % T
% Val: 0 0 0 8 0 0 8 0 0 0 0 8 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 8 0 0 8 70 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _