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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPT1
All Species:
23.94
Human Site:
T39
Identified Species:
43.89
UniProt:
P13693
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13693
NP_003286.1
172
19595
T39
E
G
K
M
V
S
R
T
E
G
N
I
D
D
S
Chimpanzee
Pan troglodytes
XP_001146432
172
19563
T39
E
G
K
M
V
S
R
T
E
G
N
I
D
D
S
Rhesus Macaque
Macaca mulatta
XP_001112392
172
19576
T39
E
G
K
M
V
S
R
T
E
G
N
I
D
D
S
Dog
Lupus familis
XP_856352
152
17083
V31
A
D
G
L
C
L
E
V
E
G
K
M
V
S
R
Cat
Felis silvestris
Mouse
Mus musculus
NP_033455
172
19444
T39
E
G
K
M
V
S
R
T
E
G
A
I
D
D
S
Rat
Rattus norvegicus
P63029
172
19444
T39
E
G
K
M
V
S
R
T
E
G
A
I
D
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P43347
172
19512
T39
E
G
K
M
V
T
R
T
E
G
Q
I
D
D
S
Frog
Xenopus laevis
Q7ZYF2
172
19508
E39
E
G
K
V
I
Q
R
E
E
G
A
I
D
D
A
Zebra Danio
Brachydanio rerio
Q9DGK4
171
19006
R38
V
E
G
K
M
I
T
R
A
E
G
D
I
D
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGS2
172
19619
R37
V
Y
G
K
L
I
T
R
Q
G
D
D
I
K
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q8H6A5
167
18672
T37
E
V
E
G
K
W
V
T
Q
G
P
V
D
V
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P35691
167
18723
V35
Y
E
A
D
C
A
M
V
N
V
G
G
D
N
I
Red Bread Mold
Neurospora crassa
Q7RYV5
170
19009
G38
D
C
A
M
I
E
E
G
A
V
Q
V
D
I
G
Conservation
Percent
Protein Identity:
100
99.4
99.4
88.3
N.A.
95.9
95.9
N.A.
N.A.
90.1
68.5
67.4
N.A.
50.5
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
100
88.3
N.A.
98.8
98.8
N.A.
N.A.
97
80.2
83.7
N.A.
70.9
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
13.3
N.A.
93.3
93.3
N.A.
N.A.
86.6
60
6.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
26.6
N.A.
93.3
93.3
N.A.
N.A.
93.3
80
13.3
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
39.5
N.A.
N.A.
41.8
45.9
Protein Similarity:
N.A.
57.5
N.A.
N.A.
63.9
66.2
P-Site Identity:
N.A.
26.6
N.A.
N.A.
6.6
13.3
P-Site Similarity:
N.A.
46.6
N.A.
N.A.
20
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
16
0
0
8
0
0
16
0
24
0
0
0
8
% A
% Cys:
0
8
0
0
16
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
8
0
0
0
0
0
0
8
16
77
62
16
% D
% Glu:
62
16
8
0
0
8
16
8
62
8
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
54
24
8
0
0
0
8
0
77
16
8
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
16
16
0
0
0
0
0
54
16
8
8
% I
% Lys:
0
0
54
16
8
0
0
0
0
0
8
0
0
8
0
% K
% Leu:
0
0
0
8
8
8
0
0
0
0
0
0
0
0
8
% L
% Met:
0
0
0
54
8
0
8
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
24
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
16
0
16
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
54
16
0
0
0
0
0
0
8
% R
% Ser:
0
0
0
0
0
39
0
0
0
0
0
0
0
8
47
% S
% Thr:
0
0
0
0
0
8
16
54
0
0
0
0
0
0
0
% T
% Val:
16
8
0
8
47
0
8
16
0
16
0
16
8
8
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _