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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPT1
All Species:
39.7
Human Site:
Y18
Identified Species:
72.78
UniProt:
P13693
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13693
NP_003286.1
172
19595
Y18
D
E
M
F
S
D
I
Y
K
I
R
E
I
A
D
Chimpanzee
Pan troglodytes
XP_001146432
172
19563
Y18
D
E
M
F
S
D
I
Y
K
I
R
E
I
A
D
Rhesus Macaque
Macaca mulatta
XP_001112392
172
19576
Y18
D
E
M
F
S
D
I
Y
K
I
R
E
I
A
D
Dog
Lupus familis
XP_856352
152
17083
F14
L
I
S
H
D
E
M
F
S
D
I
Y
K
I
R
Cat
Felis silvestris
Mouse
Mus musculus
NP_033455
172
19444
Y18
D
E
L
F
S
D
I
Y
K
I
R
E
I
A
D
Rat
Rattus norvegicus
P63029
172
19444
Y18
D
E
L
F
S
D
I
Y
K
I
R
E
I
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P43347
172
19512
Y18
D
E
M
F
S
D
I
Y
K
I
R
E
V
A
N
Frog
Xenopus laevis
Q7ZYF2
172
19508
Y18
D
E
M
F
S
D
I
Y
K
I
I
E
T
P
D
Zebra Danio
Brachydanio rerio
Q9DGK4
171
19006
Y18
D
E
M
F
S
D
I
Y
K
I
K
E
S
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGS2
172
19619
Y18
D
E
M
F
A
D
T
Y
K
M
K
L
V
D
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q8H6A5
167
18672
F18
D
E
L
L
S
D
S
F
T
Y
K
E
L
E
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P35691
167
18723
Y18
D
E
L
L
S
D
A
Y
D
A
K
L
V
D
D
Red Bread Mold
Neurospora crassa
Q7RYV5
170
19009
Y18
D
E
I
I
S
D
S
Y
D
L
K
E
V
D
G
Conservation
Percent
Protein Identity:
100
99.4
99.4
88.3
N.A.
95.9
95.9
N.A.
N.A.
90.1
68.5
67.4
N.A.
50.5
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
100
88.3
N.A.
98.8
98.8
N.A.
N.A.
97
80.2
83.7
N.A.
70.9
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
93.3
93.3
N.A.
N.A.
86.6
80
73.3
N.A.
53.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
100
100
N.A.
N.A.
100
80
86.6
N.A.
80
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
39.5
N.A.
N.A.
41.8
45.9
Protein Similarity:
N.A.
57.5
N.A.
N.A.
63.9
66.2
P-Site Identity:
N.A.
33.3
N.A.
N.A.
40
40
P-Site Similarity:
N.A.
66.6
N.A.
N.A.
60
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
8
0
0
8
0
0
0
47
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
93
0
0
0
8
93
0
0
16
8
0
0
0
24
62
% D
% Glu:
0
93
0
0
0
8
0
0
0
0
0
77
0
16
0
% E
% Phe:
0
0
0
70
0
0
0
16
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
8
8
0
0
62
0
0
62
16
0
39
8
0
% I
% Lys:
0
0
0
0
0
0
0
0
70
0
39
0
8
0
0
% K
% Leu:
8
0
31
16
0
0
0
0
0
8
0
16
8
0
0
% L
% Met:
0
0
54
0
0
0
8
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
24
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
47
0
0
0
8
% R
% Ser:
0
0
8
0
85
0
16
0
8
0
0
0
8
0
0
% S
% Thr:
0
0
0
0
0
0
8
0
8
0
0
0
8
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
31
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
85
0
8
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _