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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALAD
All Species:
24.85
Human Site:
S136
Identified Species:
42.05
UniProt:
P13716
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13716
NP_000022.3
330
36295
S136
H
G
H
C
G
L
L
S
E
N
G
A
F
R
A
Chimpanzee
Pan troglodytes
XP_520202
339
37211
S145
H
G
H
C
G
L
L
S
E
N
G
A
F
R
A
Rhesus Macaque
Macaca mulatta
XP_001101576
339
37161
S145
H
G
H
C
G
L
L
S
E
N
G
A
F
R
A
Dog
Lupus familis
XP_855370
330
36083
S136
H
G
H
C
G
L
L
S
K
N
G
A
F
L
A
Cat
Felis silvestris
Mouse
Mus musculus
P10518
330
36005
S136
H
G
H
C
G
L
L
S
E
N
G
A
F
L
A
Rat
Rattus norvegicus
P06214
330
36013
S136
H
G
H
C
G
L
L
S
E
N
G
A
F
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507056
330
35834
R136
H
G
H
C
G
L
L
R
K
D
G
S
I
R
A
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086315
330
36193
R136
H
G
H
C
G
I
L
R
E
D
G
S
I
Q
N
Zebra Danio
Brachydanio rerio
NP_001017645
331
36014
R138
H
G
H
C
G
I
L
R
E
D
G
S
L
D
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648564
327
35915
G134
H
G
H
C
G
L
L
G
E
T
G
L
E
N
G
Honey Bee
Apis mellifera
XP_397149
336
37004
N139
H
G
H
C
G
I
L
N
E
D
E
S
I
N
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782371
336
36479
N142
H
G
H
C
G
I
L
N
E
G
G
T
L
D
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SFH9
430
46672
R236
D
G
H
D
G
I
V
R
E
D
G
V
I
M
N
Baker's Yeast
Sacchar. cerevisiae
P05373
342
37722
Y147
H
G
H
C
G
V
L
Y
D
D
G
T
I
N
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97
95.2
94.5
N.A.
89
87.8
N.A.
85.4
N.A.
77.8
74.6
N.A.
60.2
57.7
N.A.
68.1
Protein Similarity:
100
97
96.7
98.1
N.A.
95.1
94.8
N.A.
93.6
N.A.
90
87.6
N.A.
75.4
76.7
N.A.
81.2
P-Site Identity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
66.6
N.A.
53.3
53.3
N.A.
60
46.6
N.A.
53.3
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
86.6
N.A.
80
73.3
N.A.
60
73.3
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.2
51.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.4
65.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
43
0
0
50
% A
% Cys:
0
0
0
93
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
0
0
0
0
8
43
0
0
0
15
0
% D
% Glu:
0
0
0
0
0
0
0
0
79
0
8
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
43
0
0
% F
% Gly:
0
100
0
0
100
0
0
8
0
8
93
0
0
0
8
% G
% His:
93
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
36
0
0
0
0
0
0
36
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
58
93
0
0
0
0
8
15
22
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
0
0
0
15
0
43
0
0
0
22
36
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
0
0
0
0
29
0
0
0
0
0
29
8
% R
% Ser:
0
0
0
0
0
0
0
43
0
0
0
29
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
8
0
15
0
0
0
% T
% Val:
0
0
0
0
0
8
8
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _