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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALAD
All Species:
56.06
Human Site:
Y257
Identified Species:
94.87
UniProt:
P13716
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13716
NP_000022.3
330
36295
Y257
M
V
K
P
G
M
P
Y
L
D
I
V
R
E
V
Chimpanzee
Pan troglodytes
XP_520202
339
37211
Y266
M
V
K
P
G
M
P
Y
L
D
I
V
R
E
V
Rhesus Macaque
Macaca mulatta
XP_001101576
339
37161
Y266
M
V
K
P
G
M
P
Y
L
D
I
V
R
E
V
Dog
Lupus familis
XP_855370
330
36083
Y257
M
V
K
P
G
M
P
Y
L
D
V
V
R
E
V
Cat
Felis silvestris
Mouse
Mus musculus
P10518
330
36005
Y257
M
V
K
P
G
L
P
Y
L
D
M
V
R
E
V
Rat
Rattus norvegicus
P06214
330
36013
Y257
M
V
K
P
G
L
P
Y
L
D
M
V
Q
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507056
330
35834
Y257
M
V
K
P
G
M
P
Y
L
D
I
V
R
E
V
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086315
330
36193
Y257
M
V
K
P
G
M
P
Y
L
D
L
V
R
D
V
Zebra Danio
Brachydanio rerio
NP_001017645
331
36014
Y259
M
V
K
P
G
L
P
Y
L
D
I
V
R
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648564
327
35915
Y253
M
V
K
P
G
M
P
Y
L
D
I
L
R
S
T
Honey Bee
Apis mellifera
XP_397149
336
37004
Y260
I
V
K
P
G
L
P
Y
L
D
V
V
R
H
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782371
336
36479
Y263
M
V
K
P
G
M
P
Y
L
D
I
V
R
D
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SFH9
430
46672
Y356
L
V
K
P
G
L
P
Y
L
D
I
I
R
L
L
Baker's Yeast
Sacchar. cerevisiae
P05373
342
37722
Y268
I
V
K
P
S
T
F
Y
L
D
I
M
R
D
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97
95.2
94.5
N.A.
89
87.8
N.A.
85.4
N.A.
77.8
74.6
N.A.
60.2
57.7
N.A.
68.1
Protein Similarity:
100
97
96.7
98.1
N.A.
95.1
94.8
N.A.
93.6
N.A.
90
87.6
N.A.
75.4
76.7
N.A.
81.2
P-Site Identity:
100
100
100
93.3
N.A.
86.6
80
N.A.
100
N.A.
86.6
93.3
N.A.
80
66.6
N.A.
86.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
N.A.
100
100
N.A.
86.6
86.6
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.2
51.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.4
65.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
66.6
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
93.3
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
100
0
0
0
22
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
58
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
93
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
15
0
0
0
0
0
0
0
0
0
65
8
0
0
0
% I
% Lys:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
0
0
0
36
0
0
100
0
8
8
0
8
8
% L
% Met:
79
0
0
0
0
58
0
0
0
0
15
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
100
0
0
93
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
93
0
0
% R
% Ser:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% S
% Thr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
22
% T
% Val:
0
100
0
0
0
0
0
0
0
0
15
79
0
0
65
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _