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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLS3
All Species:
35.15
Human Site:
Y433
Identified Species:
70.3
UniProt:
P13797
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13797
NP_001129497.1
630
70811
Y433
A
L
V
I
L
Q
L
Y
E
R
I
K
V
P
V
Chimpanzee
Pan troglodytes
XP_521227
612
68753
A430
P
H
V
N
H
L
Y
A
D
L
Q
D
A
L
V
Rhesus Macaque
Macaca mulatta
XP_001103714
639
71797
Y442
A
L
V
I
L
Q
L
Y
E
R
I
K
V
P
V
Dog
Lupus familis
XP_538147
630
70764
Y433
A
L
V
I
L
Q
L
Y
E
R
I
K
V
P
V
Cat
Felis silvestris
Mouse
Mus musculus
Q99K51
630
70723
Y433
A
L
V
I
L
Q
L
Y
E
R
I
K
V
P
V
Rat
Rattus norvegicus
Q63598
630
70661
Y433
A
L
V
I
L
Q
L
Y
E
R
I
K
V
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511237
605
67369
Y408
A
L
V
I
L
Q
L
Y
E
R
I
K
V
P
V
Chicken
Gallus gallus
P19179
630
70921
Y432
A
L
I
I
F
Q
L
Y
E
M
T
R
V
P
V
Frog
Xenopus laevis
NP_001083581
629
70942
Y431
A
L
V
I
L
Q
L
Y
D
K
I
K
V
P
V
Zebra Danio
Brachydanio rerio
Q6P698
624
69882
Y428
A
L
V
I
F
Q
L
Y
E
K
I
K
V
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q7G188
687
76910
L428
G
W
I
L
L
E
V
L
D
K
V
S
P
S
S
Baker's Yeast
Sacchar. cerevisiae
P32599
642
71754
E448
L
I
L
L
Q
A
Y
E
K
V
M
P
G
A
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.1
98.5
99.5
N.A.
99
97.9
N.A.
84.1
72.2
88.4
76.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
94.4
98.5
100
N.A.
99.8
99
N.A.
89.3
86.8
95.7
87.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
100
66.6
86.6
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
100
80
100
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.6
39.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57
61.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
75
0
0
0
0
9
0
9
0
0
0
0
9
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
25
0
0
9
0
0
0
% D
% Glu:
0
0
0
0
0
9
0
9
67
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% G
% His:
0
9
0
0
9
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
17
75
0
0
0
0
0
0
67
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
9
25
0
67
0
0
0
% K
% Leu:
9
75
9
17
67
9
75
9
0
9
0
0
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
9
9
0
0
0
0
% M
% Asn:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
9
0
0
0
0
0
0
0
0
0
0
9
9
75
0
% P
% Gln:
0
0
0
0
9
75
0
0
0
0
9
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
50
0
9
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
9
0
9
9
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% T
% Val:
0
0
75
0
0
0
9
0
0
9
9
0
75
0
92
% V
% Trp:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
17
75
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _