KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APEH
All Species:
30
Human Site:
Y145
Identified Species:
73.33
UniProt:
P13798
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13798
NP_001631.3
732
81225
Y145
L
E
K
H
G
P
V
Y
E
D
D
C
F
G
C
Chimpanzee
Pan troglodytes
XP_001165626
732
81178
Y145
L
E
K
H
G
P
V
Y
E
D
D
C
F
G
C
Rhesus Macaque
Macaca mulatta
XP_001108167
732
81361
Y145
L
E
K
H
G
P
V
Y
E
D
D
C
F
G
C
Dog
Lupus familis
XP_533826
732
81431
Y145
L
E
K
H
G
L
V
Y
E
D
D
C
F
G
C
Cat
Felis silvestris
Mouse
Mus musculus
Q8R146
732
81503
Y145
L
E
K
H
G
P
V
Y
E
D
D
C
F
G
C
Rat
Rattus norvegicus
P13676
732
81365
Y145
L
E
K
H
G
P
V
Y
E
D
D
C
F
G
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520342
683
76275
K144
S
D
E
T
P
R
M
K
K
E
D
S
T
V
K
Chicken
Gallus gallus
NP_001025756
734
81216
Y146
L
D
K
H
G
S
V
Y
D
D
N
Q
F
G
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002663312
742
83007
Y154
L
N
K
H
G
K
V
Y
E
D
D
Q
F
G
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001123355
635
71958
D111
N
Y
D
L
A
A
L
D
V
H
G
D
V
Y
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.7
93.8
N.A.
91.2
92.2
N.A.
68
64.9
N.A.
59.5
N.A.
N.A.
30.8
N.A.
N.A.
Protein Similarity:
100
100
99.5
96.9
N.A.
95.4
95.7
N.A.
78.9
79.2
N.A.
74.1
N.A.
N.A.
48.7
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
6.6
66.6
N.A.
80
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
40
86.6
N.A.
80
N.A.
N.A.
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
60
0
0
80
% C
% Asp:
0
20
10
0
0
0
0
10
10
80
80
10
0
0
0
% D
% Glu:
0
60
10
0
0
0
0
0
70
10
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
80
0
0
% F
% Gly:
0
0
0
0
80
0
0
0
0
0
10
0
0
80
0
% G
% His:
0
0
0
80
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
80
0
0
10
0
10
10
0
0
0
0
0
10
% K
% Leu:
80
0
0
10
0
10
10
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
10
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
0
0
10
50
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% Q
% Arg:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% S
% Thr:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
10
% T
% Val:
0
0
0
0
0
0
80
0
10
0
0
0
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
80
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _