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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ETFA
All Species:
39.39
Human Site:
S140
Identified Species:
61.9
UniProt:
P13804
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13804
NP_000117.1
333
35080
S140
S
D
I
I
A
I
K
S
P
D
T
F
V
R
T
Chimpanzee
Pan troglodytes
XP_510690
333
35147
S140
S
D
I
I
A
I
K
S
P
D
T
F
V
R
T
Rhesus Macaque
Macaca mulatta
XP_001104838
333
35063
S140
S
D
I
I
A
I
K
S
P
D
T
F
V
R
T
Dog
Lupus familis
XP_853387
333
34979
S140
S
D
I
I
A
I
K
S
P
D
T
F
V
R
T
Cat
Felis silvestris
Mouse
Mus musculus
Q99LC5
333
34991
S140
S
D
I
I
E
I
K
S
P
D
T
F
V
R
T
Rat
Rattus norvegicus
P13803
333
34933
S140
S
D
I
I
E
I
K
S
P
D
T
F
V
R
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001025714
346
36718
S141
S
D
I
I
E
I
K
S
P
N
T
F
V
R
T
Frog
Xenopus laevis
NP_001090035
333
35093
S140
S
D
V
I
E
I
K
S
P
D
T
F
V
R
T
Zebra Danio
Brachydanio rerio
NP_944591
333
35072
S141
S
D
I
I
E
I
K
S
P
D
T
F
V
R
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_476975
330
34163
D140
E
I
I
D
V
K
S
D
D
T
F
V
R
T
I
Honey Bee
Apis mellifera
XP_624102
333
35360
S143
D
I
I
D
I
K
S
S
D
T
F
I
R
T
I
Nematode Worm
Caenorhab. elegans
Q93615
332
34436
S141
S
D
V
T
E
V
H
S
A
D
S
F
T
R
T
Sea Urchin
Strong. purpuratus
XP_801964
336
35359
A143
S
D
I
I
D
I
K
A
P
D
T
F
V
R
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C6I6
363
38389
Y169
D
Q
F
I
R
P
I
Y
A
G
N
A
L
C
T
Baker's Yeast
Sacchar. cerevisiae
Q12480
344
36784
D147
C
E
V
T
V
I
K
D
P
K
T
F
I
R
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.5
94.5
N.A.
95.8
95.1
N.A.
N.A.
79.4
77.7
80.4
N.A.
69
67.2
61.2
67.8
Protein Similarity:
100
99.6
99.4
97.5
N.A.
97.3
96.6
N.A.
N.A.
87.5
88.5
90
N.A.
81.6
81.6
75
83.6
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
86.6
86.6
93.3
N.A.
6.6
13.3
46.6
86.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
93.3
93.3
93.3
N.A.
6.6
13.3
66.6
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.5
45.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
65.2
65.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
27
0
0
7
14
0
0
7
0
0
0
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% C
% Asp:
14
74
0
14
7
0
0
14
14
67
0
0
0
0
0
% D
% Glu:
7
7
0
0
40
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
7
0
0
0
0
0
0
0
14
80
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% H
% Ile:
0
14
74
74
7
74
7
0
0
0
0
7
7
0
14
% I
% Lys:
0
0
0
0
0
14
74
0
0
7
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
7
7
0
0
0
0
% N
% Pro:
0
0
0
0
0
7
0
0
74
0
0
0
0
0
7
% P
% Gln:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
7
0
0
0
0
0
0
0
14
80
0
% R
% Ser:
74
0
0
0
0
0
14
74
0
0
7
0
0
0
0
% S
% Thr:
0
0
0
14
0
0
0
0
0
14
74
0
7
14
80
% T
% Val:
0
0
20
0
14
7
0
0
0
0
0
7
67
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _