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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ETFA All Species: 31.21
Human Site: S184 Identified Species: 49.05
UniProt: P13804 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P13804 NP_000117.1 333 35080 S184 A T S G G S A S S E K A S S T
Chimpanzee Pan troglodytes XP_510690 333 35147 S184 A T S G G S A S S E K A S S T
Rhesus Macaque Macaca mulatta XP_001104838 333 35063 S184 A T S G G T A S S E K A S S T
Dog Lupus familis XP_853387 333 34979 S184 A T S G G S A S S E K A S S T
Cat Felis silvestris
Mouse Mus musculus Q99LC5 333 34991 S184 A T S G G S A S S E K A P S S
Rat Rattus norvegicus P13803 333 34933 S184 A A S G G S A S S E K A P S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001025714 346 36718 S185 P T S G G S A S V E K V T P P
Frog Xenopus laevis NP_001090035 333 35093 S184 P A S G G S A S S D T V A P S
Zebra Danio Brachydanio rerio NP_944591 333 35072 T185 A A D G G S S T S E E V S P S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_476975 330 34163 V184 T S G G S G A V E Q A P A G D
Honey Bee Apis mellifera XP_624102 333 35360 C187 L E G G N A K C E A A P A G D
Nematode Worm Caenorhab. elegans Q93615 332 34436 V185 K E G G S G A V E N A P S A D
Sea Urchin Strong. purpuratus XP_801964 336 35359 A187 E A T G G A G A S E P A P A C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C6I6 363 38389 I213 K K A T V S Q I D L S N F E D
Baker's Yeast Sacchar. cerevisiae Q12480 344 36784 V191 A E G S M D S V T I E K R T D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98.5 94.5 N.A. 95.8 95.1 N.A. N.A. 79.4 77.7 80.4 N.A. 69 67.2 61.2 67.8
Protein Similarity: 100 99.6 99.4 97.5 N.A. 97.3 96.6 N.A. N.A. 87.5 88.5 90 N.A. 81.6 81.6 75 83.6
P-Site Identity: 100 100 93.3 100 N.A. 86.6 80 N.A. N.A. 60 46.6 46.6 N.A. 13.3 6.6 20 33.3
P-Site Similarity: 100 100 100 100 N.A. 93.3 86.6 N.A. N.A. 66.6 66.6 73.3 N.A. 33.3 20 26.6 60
Percent
Protein Identity: N.A. N.A. N.A. 46.5 45.3 N.A.
Protein Similarity: N.A. N.A. N.A. 65.2 65.1 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 54 27 7 0 0 14 67 7 0 7 20 47 20 14 0 % A
% Cys: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 7 % C
% Asp: 0 0 7 0 0 7 0 0 7 7 0 0 0 0 34 % D
% Glu: 7 20 0 0 0 0 0 0 20 60 14 0 0 7 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % F
% Gly: 0 0 27 87 67 14 7 0 0 0 0 0 0 14 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 7 0 7 0 0 0 0 0 % I
% Lys: 14 7 0 0 0 0 7 0 0 0 47 7 0 0 0 % K
% Leu: 7 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % L
% Met: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 7 0 0 0 0 7 0 7 0 0 0 % N
% Pro: 14 0 0 0 0 0 0 0 0 0 7 20 20 20 7 % P
% Gln: 0 0 0 0 0 0 7 0 0 7 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % R
% Ser: 0 7 54 7 14 60 14 54 60 0 7 0 40 40 27 % S
% Thr: 7 40 7 7 0 7 0 7 7 0 7 0 7 7 27 % T
% Val: 0 0 0 0 7 0 0 20 7 0 0 20 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _