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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ETFA
All Species:
20.91
Human Site:
S189
Identified Species:
32.86
UniProt:
P13804
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13804
NP_000117.1
333
35080
S189
S
A
S
S
E
K
A
S
S
T
S
P
V
E
I
Chimpanzee
Pan troglodytes
XP_510690
333
35147
S189
S
A
S
S
E
K
A
S
S
T
S
P
V
E
I
Rhesus Macaque
Macaca mulatta
XP_001104838
333
35063
S189
T
A
S
S
E
K
A
S
S
T
S
P
V
E
I
Dog
Lupus familis
XP_853387
333
34979
S189
S
A
S
S
E
K
A
S
S
T
S
S
V
G
I
Cat
Felis silvestris
Mouse
Mus musculus
Q99LC5
333
34991
P189
S
A
S
S
E
K
A
P
S
S
S
S
V
G
I
Rat
Rattus norvegicus
P13803
333
34933
P189
S
A
S
S
E
K
A
P
S
S
S
S
A
G
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001025714
346
36718
T190
S
A
S
V
E
K
V
T
P
P
P
P
V
G
L
Frog
Xenopus laevis
NP_001090035
333
35093
A189
S
A
S
S
D
T
V
A
P
S
A
P
V
G
L
Zebra Danio
Brachydanio rerio
NP_944591
333
35072
S190
S
S
T
S
E
E
V
S
P
S
A
P
V
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_476975
330
34163
A189
G
A
V
E
Q
A
P
A
G
D
F
A
S
S
L
Honey Bee
Apis mellifera
XP_624102
333
35360
A192
A
K
C
E
A
A
P
A
G
D
Y
K
S
E
L
Nematode Worm
Caenorhab. elegans
Q93615
332
34436
S190
G
A
V
E
N
A
P
S
A
D
I
K
T
D
L
Sea Urchin
Strong. purpuratus
XP_801964
336
35359
P192
A
G
A
S
E
P
A
P
A
C
D
V
K
N
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C6I6
363
38389
F218
S
Q
I
D
L
S
N
F
E
D
D
S
V
S
K
Baker's Yeast
Sacchar. cerevisiae
Q12480
344
36784
R196
D
S
V
T
I
E
K
R
T
D
I
P
P
C
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.5
94.5
N.A.
95.8
95.1
N.A.
N.A.
79.4
77.7
80.4
N.A.
69
67.2
61.2
67.8
Protein Similarity:
100
99.6
99.4
97.5
N.A.
97.3
96.6
N.A.
N.A.
87.5
88.5
90
N.A.
81.6
81.6
75
83.6
P-Site Identity:
100
100
93.3
86.6
N.A.
73.3
66.6
N.A.
N.A.
46.6
40
40
N.A.
6.6
6.6
13.3
20
P-Site Similarity:
100
100
100
86.6
N.A.
80
73.3
N.A.
N.A.
60
73.3
80
N.A.
26.6
26.6
33.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.5
45.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
65.2
65.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
67
7
0
7
20
47
20
14
0
14
7
7
0
0
% A
% Cys:
0
0
7
0
0
0
0
0
0
7
0
0
0
7
0
% C
% Asp:
7
0
0
7
7
0
0
0
0
34
14
0
0
7
14
% D
% Glu:
0
0
0
20
60
14
0
0
7
0
0
0
0
27
0
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
7
0
0
0
0
% F
% Gly:
14
7
0
0
0
0
0
0
14
0
0
0
0
40
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
0
7
0
0
0
0
0
14
0
0
0
40
% I
% Lys:
0
7
0
0
0
47
7
0
0
0
0
14
7
0
7
% K
% Leu:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
34
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
7
0
7
0
0
0
0
0
0
7
0
% N
% Pro:
0
0
0
0
0
7
20
20
20
7
7
47
7
0
0
% P
% Gln:
0
7
0
0
7
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% R
% Ser:
60
14
54
60
0
7
0
40
40
27
40
27
14
14
0
% S
% Thr:
7
0
7
7
0
7
0
7
7
27
0
0
7
0
0
% T
% Val:
0
0
20
7
0
0
20
0
0
0
0
7
60
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _