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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ETFA
All Species:
46.97
Human Site:
Y149
Identified Species:
73.81
UniProt:
P13804
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13804
NP_000117.1
333
35080
Y149
D
T
F
V
R
T
I
Y
A
G
N
A
L
C
T
Chimpanzee
Pan troglodytes
XP_510690
333
35147
Y149
D
T
F
V
R
T
I
Y
A
G
N
A
L
C
T
Rhesus Macaque
Macaca mulatta
XP_001104838
333
35063
Y149
D
T
F
V
R
T
I
Y
A
G
N
A
L
C
T
Dog
Lupus familis
XP_853387
333
34979
Y149
D
T
F
V
R
T
I
Y
A
G
N
A
I
C
T
Cat
Felis silvestris
Mouse
Mus musculus
Q99LC5
333
34991
Y149
D
T
F
V
R
T
I
Y
A
G
N
A
L
C
T
Rat
Rattus norvegicus
P13803
333
34933
Y149
D
T
F
V
R
T
I
Y
A
G
N
A
L
C
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001025714
346
36718
Y150
N
T
F
V
R
T
I
Y
A
G
N
V
L
C
T
Frog
Xenopus laevis
NP_001090035
333
35093
Y149
D
T
F
V
R
T
I
Y
A
G
N
A
L
C
T
Zebra Danio
Brachydanio rerio
NP_944591
333
35072
Y150
D
T
F
V
R
T
I
Y
A
G
N
A
L
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_476975
330
34163
A149
T
F
V
R
T
I
Y
A
G
N
A
I
L
T
L
Honey Bee
Apis mellifera
XP_624102
333
35360
A152
T
F
I
R
T
I
Y
A
G
N
A
I
Q
T
L
Nematode Worm
Caenorhab. elegans
Q93615
332
34436
Y150
D
S
F
T
R
T
L
Y
A
G
N
A
V
K
K
Sea Urchin
Strong. purpuratus
XP_801964
336
35359
Y152
D
T
F
V
R
T
I
Y
A
G
N
A
I
A
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C6I6
363
38389
R178
G
N
A
L
C
T
V
R
Y
T
G
A
G
P
C
Baker's Yeast
Sacchar. cerevisiae
Q12480
344
36784
Y156
K
T
F
I
R
P
I
Y
A
G
N
I
I
S
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.5
94.5
N.A.
95.8
95.1
N.A.
N.A.
79.4
77.7
80.4
N.A.
69
67.2
61.2
67.8
Protein Similarity:
100
99.6
99.4
97.5
N.A.
97.3
96.6
N.A.
N.A.
87.5
88.5
90
N.A.
81.6
81.6
75
83.6
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
86.6
100
93.3
N.A.
6.6
0
60
86.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
93.3
100
93.3
N.A.
6.6
0
80
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.5
45.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
65.2
65.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
0
0
14
80
0
14
74
0
7
0
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
0
0
0
54
7
% C
% Asp:
67
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
14
80
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
0
0
0
0
0
0
0
14
80
7
0
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
7
0
14
74
0
0
0
0
20
20
0
0
% I
% Lys:
7
0
0
0
0
0
0
0
0
0
0
0
0
7
7
% K
% Leu:
0
0
0
7
0
0
7
0
0
0
0
0
60
0
14
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
7
0
0
0
0
0
0
0
14
80
0
0
0
0
% N
% Pro:
0
0
0
0
0
7
0
0
0
0
0
0
0
7
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% Q
% Arg:
0
0
0
14
80
0
0
7
0
0
0
0
0
0
0
% R
% Ser:
0
7
0
0
0
0
0
0
0
0
0
0
0
14
0
% S
% Thr:
14
74
0
7
14
80
0
0
0
7
0
0
0
14
74
% T
% Val:
0
0
7
67
0
0
7
0
0
0
0
7
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
14
80
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _