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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNNT1
All Species:
8.79
Human Site:
S187
Identified Species:
17.58
UniProt:
P13805
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13805
NP_001119604.1
278
32948
S187
E
M
K
V
R
I
L
S
E
R
K
K
P
L
D
Chimpanzee
Pan troglodytes
XP_001134698
245
28524
S149
E
R
I
E
R
R
R
S
E
R
A
E
Q
Q
R
Rhesus Macaque
Macaca mulatta
XP_001085351
277
32898
S186
E
M
K
L
R
I
L
S
E
R
K
K
P
L
D
Dog
Lupus familis
XP_533586
243
28859
K152
Y
L
V
K
A
E
Q
K
R
G
K
R
Q
T
G
Cat
Felis silvestris
Mouse
Mus musculus
O88346
262
31326
K171
Y
L
V
K
A
E
Q
K
R
G
K
R
Q
T
G
Rat
Rattus norvegicus
Q7TNB2
261
31197
K170
Y
L
V
K
A
E
Q
K
R
G
K
R
Q
T
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516242
219
26174
K128
Y
L
V
K
A
E
Q
K
R
G
K
R
Q
T
G
Chicken
Gallus gallus
P12620
263
31123
K171
Y
L
A
K
A
D
Q
K
R
G
K
K
Q
T
A
Frog
Xenopus laevis
NP_001086207
265
31916
K174
Y
L
V
K
A
E
Q
K
R
G
K
K
Q
T
G
Zebra Danio
Brachydanio rerio
Q1RM03
499
62332
E414
E
E
L
L
Q
Q
L
E
Q
D
R
L
T
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P19351
397
47429
S181
E
E
K
K
I
S
L
S
F
R
I
K
P
L
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27371
405
47023
D200
A
Q
A
K
G
G
K
D
V
M
S
K
E
Q
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.2
97.4
82.7
N.A.
89.5
89.2
N.A.
72.6
59.3
75.5
20.6
N.A.
24.6
N.A.
27.1
N.A.
Protein Similarity:
100
65.8
98.5
84.8
N.A.
92.4
92
N.A.
76.6
74.4
83.8
34.2
N.A.
38.2
N.A.
40.4
N.A.
P-Site Identity:
100
33.3
93.3
6.6
N.A.
6.6
6.6
N.A.
6.6
13.3
13.3
20
N.A.
53.3
N.A.
6.6
N.A.
P-Site Similarity:
100
40
100
20
N.A.
20
20
N.A.
20
20
20
46.6
N.A.
53.3
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
17
0
50
0
0
0
0
0
9
0
0
0
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
9
0
9
0
9
0
0
0
0
17
% D
% Glu:
42
17
0
9
0
42
0
9
25
0
0
9
9
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
9
9
0
0
0
50
0
0
0
0
42
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
9
17
0
0
0
0
9
0
0
0
0
% I
% Lys:
0
0
25
67
0
0
9
50
0
0
67
50
0
0
0
% K
% Leu:
0
50
9
17
0
0
34
0
0
0
0
9
0
34
0
% L
% Met:
0
17
0
0
0
0
0
0
0
9
0
0
0
0
9
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
25
0
0
% P
% Gln:
0
9
0
0
9
9
50
0
9
0
0
0
59
17
0
% Q
% Arg:
0
9
0
0
25
9
9
0
50
34
9
34
0
0
17
% R
% Ser:
0
0
0
0
0
9
0
34
0
0
9
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
9
50
0
% T
% Val:
0
0
42
9
0
0
0
0
9
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
50
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _