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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GYS1
All Species:
4.55
Human Site:
S698
Identified Species:
7.14
UniProt:
P13807
Number Species:
14
Phosphosite Substitution
Charge Score:
0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13807
NP_002094.2
737
83786
S698
P
E
W
P
R
R
A
S
C
T
S
S
T
S
G
Chimpanzee
Pan troglodytes
XP_520790
703
80912
E664
S
D
V
E
D
E
V
E
D
E
R
Y
D
E
E
Rhesus Macaque
Macaca mulatta
Q8MJ26
737
83768
S698
P
E
W
P
R
R
A
S
C
T
S
S
T
S
G
Dog
Lupus familis
XP_534869
703
80957
E664
S
D
V
E
D
E
E
E
D
E
R
Y
N
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1E4
738
83908
C699
E
W
P
R
R
A
S
C
S
S
S
T
G
G
S
Rat
Rattus norvegicus
A2RRU1
738
84053
C699
E
W
P
R
R
A
S
C
S
S
S
T
G
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505471
733
83148
P694
E
W
Q
R
R
P
S
P
G
L
L
A
Q
S
G
Chicken
Gallus gallus
XP_416432
704
81032
D662
P
H
Q
S
E
G
E
D
E
D
E
D
E
R
Y
Frog
Xenopus laevis
NP_001084863
702
80811
D663
H
D
S
E
E
E
D
D
E
E
R
Y
D
E
D
Zebra Danio
Brachydanio rerio
NP_957474
700
80455
E662
H
H
S
E
A
E
D
E
E
E
P
Y
D
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VFC8
709
81735
N663
S
L
Y
G
S
K
N
N
L
I
F
S
R
P
H
Honey Bee
Apis mellifera
XP_624707
692
79590
P654
P
R
P
I
S
E
P
P
S
P
S
S
S
R
H
Nematode Worm
Caenorhab. elegans
Q9U2D9
672
76441
L634
R
D
C
R
R
L
A
L
E
R
L
H
P
D
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P23337
708
80492
D670
T
V
Y
M
T
P
G
D
L
G
T
L
Q
D
A
Red Bread Mold
Neurospora crassa
O93869
706
80888
K668
T
E
D
Y
V
A
W
K
L
P
E
E
E
D
P
Conservation
Percent
Protein Identity:
100
68.6
99
69.3
N.A.
96.6
96.6
N.A.
90
71
69.3
78.1
N.A.
55
56.4
49.6
N.A.
Protein Similarity:
100
81.8
99.5
82.5
N.A.
98.5
98.5
N.A.
95.2
84.1
82.5
86.5
N.A.
71
70.1
65.8
N.A.
P-Site Identity:
100
0
100
0
N.A.
13.3
13.3
N.A.
20
6.6
0
0
N.A.
6.6
20
13.3
N.A.
P-Site Similarity:
100
6.6
100
6.6
N.A.
33.3
33.3
N.A.
33.3
6.6
6.6
0
N.A.
26.6
26.6
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
50
51.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
67.1
67
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
20
20
0
0
0
0
7
0
0
7
% A
% Cys:
0
0
7
0
0
0
0
14
14
0
0
0
0
0
0
% C
% Asp:
0
27
7
0
14
0
14
20
14
7
0
7
20
20
14
% D
% Glu:
20
20
0
27
14
34
14
20
27
27
14
7
14
27
14
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% F
% Gly:
0
0
0
7
0
7
7
0
7
7
0
0
14
14
20
% G
% His:
14
14
0
0
0
0
0
0
0
0
0
7
0
0
14
% H
% Ile:
0
0
0
7
0
0
0
0
0
7
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
7
0
7
0
0
0
0
0
0
0
% K
% Leu:
0
7
0
0
0
7
0
7
20
7
14
7
0
0
0
% L
% Met:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
7
7
0
0
0
0
7
0
0
% N
% Pro:
27
0
20
14
0
14
7
14
0
14
7
0
7
7
7
% P
% Gln:
0
0
14
0
0
0
0
0
0
0
0
0
14
0
0
% Q
% Arg:
7
7
0
27
40
14
0
0
0
7
20
0
7
14
0
% R
% Ser:
20
0
14
7
14
0
20
14
20
14
34
27
7
20
14
% S
% Thr:
14
0
0
0
7
0
0
0
0
14
7
14
14
0
0
% T
% Val:
0
7
14
0
7
0
7
0
0
0
0
0
0
0
7
% V
% Trp:
0
20
14
0
0
0
7
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
14
7
0
0
0
0
0
0
0
27
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _