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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GYS1 All Species: 12.73
Human Site: S702 Identified Species: 20
UniProt: P13807 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P13807 NP_002094.2 737 83786 S702 R R A S C T S S T S G S K R N
Chimpanzee Pan troglodytes XP_520790 703 80912 Y668 D E V E D E R Y D E E E E A E
Rhesus Macaque Macaca mulatta Q8MJ26 737 83768 S702 R R A S C T S S T S G S K R N
Dog Lupus familis XP_534869 703 80957 Y668 D E E E D E R Y N E E E E A E
Cat Felis silvestris
Mouse Mus musculus Q9Z1E4 738 83908 T703 R A S C S S S T G G S K R S N
Rat Rattus norvegicus A2RRU1 738 84053 T703 R A S C S S S T G G S K R S N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505471 733 83148 A698 R P S P G L L A Q S G A K R G
Chicken Gallus gallus XP_416432 704 81032 D666 E G E D E D E D E R Y D E D E
Frog Xenopus laevis NP_001084863 702 80811 Y667 E E D D E E R Y D E D E E A E
Zebra Danio Brachydanio rerio NP_957474 700 80455 Y666 A E D E E E P Y D E D L E A E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VFC8 709 81735 S667 S K N N L I F S R P H S E P P
Honey Bee Apis mellifera XP_624707 692 79590 S658 S E P P S P S S S R H T T P A
Nematode Worm Caenorhab. elegans Q9U2D9 672 76441 H638 R L A L E R L H P D V D K I M
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P23337 708 80492 L674 T P G D L G T L Q D A N N A D
Red Bread Mold Neurospora crassa O93869 706 80888 E672 V A W K L P E E E D P E E Y P
Conservation
Percent
Protein Identity: 100 68.6 99 69.3 N.A. 96.6 96.6 N.A. 90 71 69.3 78.1 N.A. 55 56.4 49.6 N.A.
Protein Similarity: 100 81.8 99.5 82.5 N.A. 98.5 98.5 N.A. 95.2 84.1 82.5 86.5 N.A. 71 70.1 65.8 N.A.
P-Site Identity: 100 0 100 0 N.A. 20 20 N.A. 33.3 0 0 0 N.A. 13.3 13.3 20 N.A.
P-Site Similarity: 100 6.6 100 6.6 N.A. 46.6 46.6 N.A. 53.3 6.6 6.6 6.6 N.A. 33.3 26.6 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 50 51.1
Protein Similarity: N.A. N.A. N.A. N.A. 67.1 67
P-Site Identity: N.A. N.A. N.A. N.A. 0 0
P-Site Similarity: N.A. N.A. N.A. N.A. 20 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 20 20 0 0 0 0 7 0 0 7 7 0 34 7 % A
% Cys: 0 0 0 14 14 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 14 0 14 20 14 7 0 7 20 20 14 14 0 7 7 % D
% Glu: 14 34 14 20 27 27 14 7 14 27 14 27 47 0 34 % E
% Phe: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % F
% Gly: 0 7 7 0 7 7 0 0 14 14 20 0 0 0 7 % G
% His: 0 0 0 0 0 0 0 7 0 0 14 0 0 0 0 % H
% Ile: 0 0 0 0 0 7 0 0 0 0 0 0 0 7 0 % I
% Lys: 0 7 0 7 0 0 0 0 0 0 0 14 27 0 0 % K
% Leu: 0 7 0 7 20 7 14 7 0 0 0 7 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % M
% Asn: 0 0 7 7 0 0 0 0 7 0 0 7 7 0 27 % N
% Pro: 0 14 7 14 0 14 7 0 7 7 7 0 0 14 14 % P
% Gln: 0 0 0 0 0 0 0 0 14 0 0 0 0 0 0 % Q
% Arg: 40 14 0 0 0 7 20 0 7 14 0 0 14 20 0 % R
% Ser: 14 0 20 14 20 14 34 27 7 20 14 20 0 14 0 % S
% Thr: 7 0 0 0 0 14 7 14 14 0 0 7 7 0 0 % T
% Val: 7 0 7 0 0 0 0 0 0 0 7 0 0 0 0 % V
% Trp: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 27 0 0 7 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _