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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GYS1 All Species: 20
Human Site: S717 Identified Species: 31.43
UniProt: P13807 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P13807 NP_002094.2 737 83786 S717 S V D T A T S S S L S T P S E
Chimpanzee Pan troglodytes XP_520790 703 80912 S683 R D R L N I K S P F S L S H V
Rhesus Macaque Macaca mulatta Q8MJ26 737 83768 S717 S V D T A T S S S L S T P S E
Dog Lupus familis XP_534869 703 80957 S683 R D R L N I K S P F S L G R V
Cat Felis silvestris
Mouse Mus musculus Q9Z1E4 738 83908 S718 S V D T G P S S S L S T P T E
Rat Rattus norvegicus A2RRU1 738 84053 S718 S V D T G P S S S L S T P T E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505471 733 83148 S713 S V D T A P S S S A S S L S E
Chicken Gallus gallus XP_416432 704 81032 N681 E A E R D R Q N I K S P F S L
Frog Xenopus laevis NP_001084863 702 80811 S682 R D R Q N I K S T F S F G P V
Zebra Danio Brachydanio rerio NP_957474 700 80455 Q681 K D R V N I R Q P Y N L P N R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VFC8 709 81735 T682 S P T S S R H T T P A P S V H
Honey Bee Apis mellifera XP_624707 692 79590 E673 A S V H G S D E E D E V D D E
Nematode Worm Caenorhab. elegans Q9U2D9 672 76441 P653 R D N E G K V P S A A T S R R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P23337 708 80492 N689 D Y F N L S T N G A I D N D D
Red Bread Mold Neurospora crassa O93869 706 80888 R687 F P L T L K Q R T G P G S P L
Conservation
Percent
Protein Identity: 100 68.6 99 69.3 N.A. 96.6 96.6 N.A. 90 71 69.3 78.1 N.A. 55 56.4 49.6 N.A.
Protein Similarity: 100 81.8 99.5 82.5 N.A. 98.5 98.5 N.A. 95.2 84.1 82.5 86.5 N.A. 71 70.1 65.8 N.A.
P-Site Identity: 100 13.3 100 13.3 N.A. 80 80 N.A. 73.3 13.3 13.3 6.6 N.A. 6.6 6.6 13.3 N.A.
P-Site Similarity: 100 13.3 100 13.3 N.A. 86.6 86.6 N.A. 80 26.6 20 20 N.A. 40 20 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 50 51.1
Protein Similarity: N.A. N.A. N.A. N.A. 67.1 67
P-Site Identity: N.A. N.A. N.A. N.A. 0 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 0 0 20 0 0 0 0 20 14 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 34 34 0 7 0 7 0 0 7 0 7 7 14 7 % D
% Glu: 7 0 7 7 0 0 0 7 7 0 7 0 0 0 40 % E
% Phe: 7 0 7 0 0 0 0 0 0 20 0 7 7 0 0 % F
% Gly: 0 0 0 0 27 0 0 0 7 7 0 7 14 0 0 % G
% His: 0 0 0 7 0 0 7 0 0 0 0 0 0 7 7 % H
% Ile: 0 0 0 0 0 27 0 0 7 0 7 0 0 0 0 % I
% Lys: 7 0 0 0 0 14 20 0 0 7 0 0 0 0 0 % K
% Leu: 0 0 7 14 14 0 0 0 0 27 0 20 7 0 14 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 7 7 27 0 0 14 0 0 7 0 7 7 0 % N
% Pro: 0 14 0 0 0 20 0 7 20 7 7 14 34 14 0 % P
% Gln: 0 0 0 7 0 0 14 7 0 0 0 0 0 0 0 % Q
% Arg: 27 0 27 7 0 14 7 7 0 0 0 0 0 14 14 % R
% Ser: 40 7 0 7 7 14 34 54 40 0 60 7 27 27 0 % S
% Thr: 0 0 7 40 0 14 7 7 20 0 0 34 0 14 0 % T
% Val: 0 34 7 7 0 0 7 0 0 0 0 7 0 7 20 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 0 0 0 0 0 0 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _