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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GYS1
All Species:
18.18
Human Site:
S730
Identified Species:
28.57
UniProt:
P13807
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13807
NP_002094.2
737
83786
S730
S
E
P
L
S
P
T
S
S
L
G
E
E
R
N
Chimpanzee
Pan troglodytes
XP_520790
703
80912
K696
H
V
P
H
G
K
K
K
L
H
G
E
Y
K
N
Rhesus Macaque
Macaca mulatta
Q8MJ26
737
83768
S730
S
E
P
L
S
P
T
S
S
L
G
E
E
R
N
Dog
Lupus familis
XP_534869
703
80957
K696
R
V
P
R
G
K
K
K
L
H
G
E
Y
K
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1E4
738
83908
S731
T
E
P
L
S
P
T
S
S
L
G
E
E
R
N
Rat
Rattus norvegicus
A2RRU1
738
84053
S731
T
E
P
L
S
P
T
S
S
L
G
E
E
R
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505471
733
83148
S726
S
E
P
V
S
P
T
S
S
L
G
E
E
R
N
Chicken
Gallus gallus
XP_416432
704
81032
G694
S
L
G
V
L
P
Q
G
K
K
K
Q
H
G
E
Frog
Xenopus laevis
NP_001084863
702
80811
K695
P
V
S
R
G
K
K
K
K
H
G
E
N
R
N
Zebra Danio
Brachydanio rerio
NP_957474
700
80455
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VFC8
709
81735
D695
V
H
G
S
D
D
E
D
S
V
D
E
E
T
E
Honey Bee
Apis mellifera
XP_624707
692
79590
Nematode Worm
Caenorhab. elegans
Q9U2D9
672
76441
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P23337
708
80492
Red Bread Mold
Neurospora crassa
O93869
706
80888
Conservation
Percent
Protein Identity:
100
68.6
99
69.3
N.A.
96.6
96.6
N.A.
90
71
69.3
78.1
N.A.
55
56.4
49.6
N.A.
Protein Similarity:
100
81.8
99.5
82.5
N.A.
98.5
98.5
N.A.
95.2
84.1
82.5
86.5
N.A.
71
70.1
65.8
N.A.
P-Site Identity:
100
26.6
100
26.6
N.A.
93.3
93.3
N.A.
93.3
13.3
26.6
0
N.A.
20
0
0
N.A.
P-Site Similarity:
100
33.3
100
33.3
N.A.
100
100
N.A.
100
26.6
26.6
0
N.A.
26.6
0
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
50
51.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
67.1
67
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
7
7
0
7
0
0
7
0
0
0
0
% D
% Glu:
0
34
0
0
0
0
7
0
0
0
0
60
40
0
14
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
14
0
20
0
0
7
0
0
54
0
0
7
0
% G
% His:
7
7
0
7
0
0
0
0
0
20
0
0
7
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
20
20
20
14
7
7
0
0
14
0
% K
% Leu:
0
7
0
27
7
0
0
0
14
34
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
54
% N
% Pro:
7
0
47
0
0
40
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
7
0
0
0
0
7
0
0
0
% Q
% Arg:
7
0
0
14
0
0
0
0
0
0
0
0
0
40
0
% R
% Ser:
27
0
7
7
34
0
0
34
40
0
0
0
0
0
0
% S
% Thr:
14
0
0
0
0
0
34
0
0
0
0
0
0
7
0
% T
% Val:
7
20
0
14
0
0
0
0
0
7
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
14
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _