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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GYS1
All Species:
30.3
Human Site:
S93
Identified Species:
47.62
UniProt:
P13807
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13807
NP_002094.2
737
83786
S93
A
L
K
R
T
L
D
S
M
N
S
K
G
C
K
Chimpanzee
Pan troglodytes
XP_520790
703
80912
A94
A
V
R
R
A
V
D
A
M
N
K
H
G
C
Q
Rhesus Macaque
Macaca mulatta
Q8MJ26
737
83768
S93
A
L
K
K
T
L
D
S
M
N
S
K
G
C
K
Dog
Lupus familis
XP_534869
703
80957
T94
A
V
R
R
A
V
D
T
M
N
K
H
G
C
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1E4
738
83908
S93
E
L
K
R
T
L
D
S
M
N
S
K
G
C
K
Rat
Rattus norvegicus
A2RRU1
738
84053
S93
E
L
K
R
T
L
D
S
M
N
S
K
G
C
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505471
733
83148
S93
A
L
K
R
T
L
D
S
M
N
S
K
G
C
K
Chicken
Gallus gallus
XP_416432
704
81032
T94
A
I
K
K
A
M
D
T
M
K
S
Q
G
C
Q
Frog
Xenopus laevis
NP_001084863
702
80811
V94
H
I
R
K
A
I
D
V
L
Q
S
Q
G
C
Q
Zebra Danio
Brachydanio rerio
NP_957474
700
80455
K93
A
L
R
R
T
I
D
K
M
N
S
S
G
C
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VFC8
709
81735
E78
S
K
A
Y
V
S
T
E
E
M
G
E
Q
L
C
Honey Bee
Apis mellifera
XP_624707
692
79590
S79
I
G
P
Y
K
E
T
S
A
R
T
E
V
E
E
Nematode Worm
Caenorhab. elegans
Q9U2D9
672
76441
S66
G
I
Y
T
V
L
R
S
K
A
Q
I
S
T
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P23337
708
80492
S82
P
I
Q
K
T
L
M
S
M
R
E
K
G
V
N
Red Bread Mold
Neurospora crassa
O93869
706
80888
A80
E
L
K
A
T
I
Q
A
M
R
D
R
G
I
G
Conservation
Percent
Protein Identity:
100
68.6
99
69.3
N.A.
96.6
96.6
N.A.
90
71
69.3
78.1
N.A.
55
56.4
49.6
N.A.
Protein Similarity:
100
81.8
99.5
82.5
N.A.
98.5
98.5
N.A.
95.2
84.1
82.5
86.5
N.A.
71
70.1
65.8
N.A.
P-Site Identity:
100
46.6
93.3
46.6
N.A.
93.3
93.3
N.A.
100
46.6
26.6
73.3
N.A.
0
6.6
13.3
N.A.
P-Site Similarity:
100
80
100
80
N.A.
93.3
93.3
N.A.
100
86.6
73.3
86.6
N.A.
13.3
26.6
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
50
51.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
67.1
67
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
40
33.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
47
0
7
7
27
0
0
14
7
7
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
67
7
% C
% Asp:
0
0
0
0
0
0
67
0
0
0
7
0
0
0
0
% D
% Glu:
20
0
0
0
0
7
0
7
7
0
7
14
0
7
14
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
7
0
0
0
0
0
0
0
0
7
0
80
0
7
% G
% His:
7
0
0
0
0
0
0
0
0
0
0
14
0
0
0
% H
% Ile:
7
27
0
0
0
20
0
0
0
0
0
7
0
7
0
% I
% Lys:
0
7
47
27
7
0
0
7
7
7
14
40
0
0
40
% K
% Leu:
0
47
0
0
0
47
0
0
7
0
0
0
0
7
0
% L
% Met:
0
0
0
0
0
7
7
0
74
7
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
54
0
0
0
0
7
% N
% Pro:
7
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
7
0
0
0
7
0
0
7
7
14
7
0
27
% Q
% Arg:
0
0
27
47
0
0
7
0
0
20
0
7
0
0
0
% R
% Ser:
7
0
0
0
0
7
0
54
0
0
54
7
7
0
0
% S
% Thr:
0
0
0
7
54
0
14
14
0
0
7
0
0
7
0
% T
% Val:
0
14
0
0
14
14
0
7
0
0
0
0
7
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
14
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _