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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GYS1
All Species:
46.36
Human Site:
T45
Identified Species:
72.86
UniProt:
P13807
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13807
NP_002094.2
737
83786
T45
N
K
V
G
G
I
Y
T
V
L
Q
T
K
A
K
Chimpanzee
Pan troglodytes
XP_520790
703
80912
T46
N
K
V
G
G
I
Y
T
V
I
Q
T
K
A
K
Rhesus Macaque
Macaca mulatta
Q8MJ26
737
83768
T45
N
K
V
G
G
I
Y
T
V
L
Q
T
K
A
K
Dog
Lupus familis
XP_534869
703
80957
T46
N
K
V
G
G
I
Y
T
V
I
Q
T
K
A
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1E4
738
83908
T45
N
K
V
G
G
I
Y
T
V
L
Q
T
K
A
K
Rat
Rattus norvegicus
A2RRU1
738
84053
T45
N
K
V
G
G
I
Y
T
V
L
Q
T
K
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505471
733
83148
T45
N
K
V
G
G
I
Y
T
V
I
Q
T
K
A
K
Chicken
Gallus gallus
XP_416432
704
81032
T46
N
K
V
G
G
I
Y
T
V
I
Q
T
K
A
K
Frog
Xenopus laevis
NP_001084863
702
80811
T46
N
K
V
G
G
I
Y
T
V
I
Q
T
K
A
K
Zebra Danio
Brachydanio rerio
NP_957474
700
80455
T45
N
K
V
G
G
I
Y
T
V
I
Q
T
K
A
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VFC8
709
81735
S30
R
R
F
S
R
V
E
S
G
A
D
L
K
D
Y
Honey Bee
Apis mellifera
XP_624707
692
79590
H31
D
R
G
Y
S
A
Q
H
E
N
R
W
Y
F
E
Nematode Worm
Caenorhab. elegans
Q9U2D9
672
76441
K18
L
S
S
N
K
I
A
K
T
I
A
G
E
D
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P23337
708
80492
V34
V
L
K
S
K
A
P
V
T
V
A
Q
Y
G
D
Red Bread Mold
Neurospora crassa
O93869
706
80888
S32
H
R
V
G
G
I
Y
S
V
L
K
S
K
A
P
Conservation
Percent
Protein Identity:
100
68.6
99
69.3
N.A.
96.6
96.6
N.A.
90
71
69.3
78.1
N.A.
55
56.4
49.6
N.A.
Protein Similarity:
100
81.8
99.5
82.5
N.A.
98.5
98.5
N.A.
95.2
84.1
82.5
86.5
N.A.
71
70.1
65.8
N.A.
P-Site Identity:
100
93.3
100
93.3
N.A.
100
100
N.A.
93.3
93.3
93.3
86.6
N.A.
6.6
0
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
26.6
26.6
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
50
51.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
67.1
67
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
60
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
93.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
14
7
0
0
7
14
0
0
74
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
0
0
0
0
0
0
7
0
0
14
7
% D
% Glu:
0
0
0
0
0
0
7
0
7
0
0
0
7
0
7
% E
% Phe:
0
0
7
0
0
0
0
0
0
0
0
0
0
7
0
% F
% Gly:
0
0
7
74
74
0
0
0
7
0
0
7
0
7
0
% G
% His:
7
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
80
0
0
0
47
0
0
0
0
0
% I
% Lys:
0
67
7
0
14
0
0
7
0
0
7
0
80
0
60
% K
% Leu:
7
7
0
0
0
0
0
0
0
34
0
7
0
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
67
0
0
7
0
0
0
0
0
7
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
7
% P
% Gln:
0
0
0
0
0
0
7
0
0
0
67
7
0
0
0
% Q
% Arg:
7
20
0
0
7
0
0
0
0
0
7
0
0
0
7
% R
% Ser:
0
7
7
14
7
0
0
14
0
0
0
7
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
67
14
0
0
67
0
0
0
% T
% Val:
7
0
74
0
0
7
0
7
74
7
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% W
% Tyr:
0
0
0
7
0
0
74
0
0
0
0
0
14
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _