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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GYS1
All Species:
17.58
Human Site:
T622
Identified Species:
27.62
UniProt:
P13807
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13807
NP_002094.2
737
83786
T622
K
A
F
P
E
H
F
T
Y
E
P
N
E
A
D
Chimpanzee
Pan troglodytes
XP_520790
703
80912
W598
R
L
S
D
L
L
D
W
R
Y
L
G
R
Y
Y
Rhesus Macaque
Macaca mulatta
Q8MJ26
737
83768
T622
K
A
F
P
E
H
F
T
Y
E
P
S
E
A
D
Dog
Lupus familis
XP_534869
703
80957
W598
R
L
S
D
L
L
D
W
R
Y
L
G
R
Y
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1E4
738
83908
T622
K
A
F
P
D
H
F
T
Y
E
P
H
E
V
D
Rat
Rattus norvegicus
A2RRU1
738
84053
T622
K
A
F
P
D
H
F
T
Y
E
P
H
E
V
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505471
733
83148
T622
K
A
F
P
D
Y
F
T
Y
E
P
H
D
A
D
Chicken
Gallus gallus
XP_416432
704
81032
L597
T
E
R
L
S
D
L
L
D
W
R
Y
L
G
R
Frog
Xenopus laevis
NP_001084863
702
80811
L597
T
E
R
L
S
D
L
L
D
W
R
Y
L
G
R
Zebra Danio
Brachydanio rerio
NP_957474
700
80455
L596
T
E
R
L
S
D
L
L
D
W
R
Y
L
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VFC8
709
81735
Q597
G
L
E
N
S
V
Q
Q
L
S
S
F
M
M
E
Honey Bee
Apis mellifera
XP_624707
692
79590
A587
A
Q
Y
M
F
D
F
A
R
L
S
R
R
Q
R
Nematode Worm
Caenorhab. elegans
Q9U2D9
672
76441
K569
H
V
E
D
H
E
Q
K
G
I
Y
V
I
D
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P23337
708
80492
E605
D
W
K
R
M
G
L
E
Y
V
K
A
R
Q
L
Red Bread Mold
Neurospora crassa
O93869
706
80888
L603
V
K
A
R
Q
L
A
L
R
R
A
Y
P
T
S
Conservation
Percent
Protein Identity:
100
68.6
99
69.3
N.A.
96.6
96.6
N.A.
90
71
69.3
78.1
N.A.
55
56.4
49.6
N.A.
Protein Similarity:
100
81.8
99.5
82.5
N.A.
98.5
98.5
N.A.
95.2
84.1
82.5
86.5
N.A.
71
70.1
65.8
N.A.
P-Site Identity:
100
0
93.3
0
N.A.
80
80
N.A.
73.3
0
0
0
N.A.
0
6.6
0
N.A.
P-Site Similarity:
100
6.6
100
6.6
N.A.
93.3
93.3
N.A.
100
0
0
0
N.A.
6.6
13.3
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
50
51.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
67.1
67
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
34
7
0
0
0
7
7
0
0
7
7
0
20
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
20
20
27
14
0
20
0
0
0
7
7
34
% D
% Glu:
0
20
14
0
14
7
0
7
0
34
0
0
27
0
7
% E
% Phe:
0
0
34
0
7
0
40
0
0
0
0
7
0
0
0
% F
% Gly:
7
0
0
0
0
7
0
0
7
0
0
14
0
20
0
% G
% His:
7
0
0
0
7
27
0
0
0
0
0
20
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
7
0
0
7
0
0
% I
% Lys:
34
7
7
0
0
0
0
7
0
0
7
0
0
0
0
% K
% Leu:
0
20
0
20
14
20
27
27
7
7
14
0
20
0
7
% L
% Met:
0
0
0
7
7
0
0
0
0
0
0
0
7
7
0
% M
% Asn:
0
0
0
7
0
0
0
0
0
0
0
7
0
0
0
% N
% Pro:
0
0
0
34
0
0
0
0
0
0
34
0
7
0
0
% P
% Gln:
0
7
0
0
7
0
14
7
0
0
0
0
0
14
0
% Q
% Arg:
14
0
20
14
0
0
0
0
27
7
20
7
27
0
34
% R
% Ser:
0
0
14
0
27
0
0
0
0
7
14
7
0
0
7
% S
% Thr:
20
0
0
0
0
0
0
34
0
0
0
0
0
7
0
% T
% Val:
7
7
0
0
0
7
0
0
0
7
0
7
0
14
0
% V
% Trp:
0
7
0
0
0
0
0
14
0
20
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
7
0
0
40
14
7
27
0
14
14
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _