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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GYS1
All Species:
18.18
Human Site:
T69
Identified Species:
28.57
UniProt:
P13807
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13807
NP_002094.2
737
83786
T69
Y
F
L
V
G
P
Y
T
E
Q
G
V
R
T
Q
Chimpanzee
Pan troglodytes
XP_520790
703
80912
F70
Y
F
L
I
G
P
Y
F
E
H
N
M
K
T
Q
Rhesus Macaque
Macaca mulatta
Q8MJ26
737
83768
T69
Y
Y
L
V
G
P
Y
T
E
Q
G
V
R
T
Q
Dog
Lupus familis
XP_534869
703
80957
F70
Y
F
L
I
G
P
Y
F
E
H
N
M
K
T
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1E4
738
83908
T69
Y
Y
L
V
G
P
Y
T
E
Q
G
V
R
T
Q
Rat
Rattus norvegicus
A2RRU1
738
84053
T69
Y
Y
L
V
G
P
Y
T
E
Q
G
V
R
T
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505471
733
83148
T69
Y
Y
L
V
G
P
Y
T
E
Q
G
V
R
T
Q
Chicken
Gallus gallus
XP_416432
704
81032
F70
Y
F
L
I
G
P
Y
F
E
H
N
V
K
T
Q
Frog
Xenopus laevis
NP_001084863
702
80811
M70
Y
F
L
M
G
P
Y
M
E
H
N
V
R
T
Q
Zebra Danio
Brachydanio rerio
NP_957474
700
80455
M69
Y
F
L
V
G
P
Y
M
E
S
N
V
R
T
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VFC8
709
81735
V54
E
N
R
W
N
F
E
V
A
W
E
V
A
N
K
Honey Bee
Apis mellifera
XP_624707
692
79590
R55
G
G
I
Y
T
V
I
R
S
K
A
Y
V
S
T
Nematode Worm
Caenorhab. elegans
Q9U2D9
672
76441
E42
A
G
Q
S
A
R
E
E
G
R
F
V
F
E
C
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P23337
708
80492
V58
K
A
T
Y
E
S
E
V
E
K
L
D
W
E
D
Red Bread Mold
Neurospora crassa
O93869
706
80888
N56
Y
T
L
I
G
P
L
N
H
Q
S
A
A
V
E
Conservation
Percent
Protein Identity:
100
68.6
99
69.3
N.A.
96.6
96.6
N.A.
90
71
69.3
78.1
N.A.
55
56.4
49.6
N.A.
Protein Similarity:
100
81.8
99.5
82.5
N.A.
98.5
98.5
N.A.
95.2
84.1
82.5
86.5
N.A.
71
70.1
65.8
N.A.
P-Site Identity:
100
60
93.3
60
N.A.
93.3
93.3
N.A.
93.3
66.6
73.3
80
N.A.
6.6
0
6.6
N.A.
P-Site Similarity:
100
80
100
80
N.A.
100
100
N.A.
100
80
80
80
N.A.
13.3
20
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
50
51.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
67.1
67
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
33.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
7
0
0
0
7
0
7
7
14
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
7
% D
% Glu:
7
0
0
0
7
0
20
7
74
0
7
0
0
14
7
% E
% Phe:
0
40
0
0
0
7
0
20
0
0
7
0
7
0
0
% F
% Gly:
7
14
0
0
74
0
0
0
7
0
34
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
7
27
0
0
0
0
0
% H
% Ile:
0
0
7
27
0
0
7
0
0
0
0
0
0
0
0
% I
% Lys:
7
0
0
0
0
0
0
0
0
14
0
0
20
0
7
% K
% Leu:
0
0
74
0
0
0
7
0
0
0
7
0
0
0
0
% L
% Met:
0
0
0
7
0
0
0
14
0
0
0
14
0
0
0
% M
% Asn:
0
7
0
0
7
0
0
7
0
0
34
0
0
7
0
% N
% Pro:
0
0
0
0
0
74
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
7
0
0
0
0
0
0
40
0
0
0
0
67
% Q
% Arg:
0
0
7
0
0
7
0
7
0
7
0
0
47
0
0
% R
% Ser:
0
0
0
7
0
7
0
0
7
7
7
0
0
7
0
% S
% Thr:
0
7
7
0
7
0
0
34
0
0
0
0
0
67
7
% T
% Val:
0
0
0
40
0
7
0
14
0
0
0
67
7
7
0
% V
% Trp:
0
0
0
7
0
0
0
0
0
7
0
0
7
0
0
% W
% Tyr:
74
27
0
14
0
0
67
0
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _